Browsing by Subject "Biological Transport"
Now showing items 1-6 of 6
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Article
A Biophysical Model of Endocannabinoid-Mediated Short Term Depression in Hippocampal Inhibition
(2013)Memories are believed to be represented in the synaptic pathways of vastly interconnected networks of neurons. The plasticity of synapses, that is, their strengthening and weakening depending on neuronal activity, is ...
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Article
Delivering nanomedicine to solid tumors
(2010)Recent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. While the enhanced permeability and retention effect has served as a key rationale for using nanoparticles to treat ...
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Article
Delivery of molecular and nanoscale medicine to tumors: Transport barriers and strategies
(2011)Tumors are similar to organs, with unique physiology giving rise to an unusual set of transport barriers to drug delivery. Cancer therapy is limited by nonuniform drug delivery via blood vessels, inhomogeneous drug transport ...
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Article
KIF1Bβ transports dendritically localized mRNPs in neurons and is recruited to synapses in an activity-dependent manner
(2013)KIF1Bβ is a kinesin-like, microtubule-based molecular motor protein involved in anterograde axonal vesicular transport in vertebrate and invertebrate neurons. Certain KIF1Bβ isoforms have been implicated in different forms ...
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Article
The origin of the Fe IV = O intermediates in cytochrome aa 3 oxidase
(2012)The dioxygen reduction mechanism in cytochrome oxidases relies on proton control of the electron transfer events that drive the process. Proton delivery and proton channels in the protein that are relevant to substrate ...
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Article
Targeting colon cancer cells with genistein-17.1A immunoconjugate.
(2003)We have shown that genistein, a major component of soy, has anti-colon cancer effects in vitro. These effects are attainable at high concentrations that are difficult to achieve in the serum. The purpose of this study was ...