Browsing by Subject "Cancer"
Now showing items 1-20 of 51
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Anxiety, depression and defense mechanisms associated with treatment decisional preferences and quality of life in non-metastatic breast cancer: A 1-year prospective study
(2013)Objective: Treatment decisional preferences impact breast cancer patients' health-related quality of life (HRQoL) and may relate to psychological variables, although many aspects of this relationship remain unknown. This ...
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Bone and soft tissue sarcomas during pregnancy: A narrative review of the literature
(2016)Bone or soft tissue sarcomas are rarely diagnosed during pregnancy. Until today 137 well documented cases have been reported in the English literature between 1963 and 2014. Thirty-eight pregnant mothers were diagnosed ...
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Cancer and pregnancy: A comprehensive review
(2011)Background: Pregnancy complicated by cancer is relatively rare but, as women in western societies tend to delay childbearing to the third and fourth decade of life, this phenomenon is going to be encountered more often in ...
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Cancer and pregnancy: Poena magna, not anymore
(2006)Cancer diagnosed during pregnancy constitutes a difficult clinical condition with a devastating impact on the patient's somatic and psychosocial health and possibly on foetal integrity. This circumstance also raises several ...
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Cancer of unknown primary (CUP)
(2005)Carcinoma of unknown primary (CUP) is one of the 10 most frequent cancers worldwide. It constitutes 3-5% of all human malignancies. Patients with CUP present with metastases without an established primary site. CUP manifests ...
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Cancer of unknown primary site: Missing primary or missing biology?
(2007)Cancer of unknown primary site (CUP) ranks as the fourth most common cause of cancer deaths and represents both a diagnostic and a management challenge. In CUP, the regression or dormancy of the primary tumor, the development ...
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Cancer prevalence and mortality in centenarians: A systematic review
(2012)Life expectancy has dramatically expanded, the global population has aged unprecedentedly and the number of centenarians has significantly increased. The analysis of autopsy series, cancer registries data, vital statistics ...
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Coexistence of pregnancy and malignancy
(2002)Cancer complicating pregnancy is a rare coexistence. The incidence is approximately 1 in 1,000 pregnancies. The most common cancers are those more frequently seen during the reproductive age of a woman. Breast cancer, ...
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A compendium of volatile organic compounds (VOCs) released by human cell lines
(2016)Volatile organic compounds (VOCs) offer unique insights into ongoing biochemical processes in healthy and diseased humans. Yet, their diagnostic use is hampered by the limited understanding of their biochemical or cellular ...
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Depression in cancer: The many biobehavioral pathways driving tumor progression
(2017)Major Depressive Disorder (MDD) is common among cancer patients, with prevalence rates up to four-times higher than the general population. Depression confers worse outcomes, including non-adherence to treatment and increased ...
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Diagnostic and therapeutic management of cancer of an unknown primary
(2003)Metastatic Cancer of Unknown Primary Site (CUP) accounts for approximately 3% of all malignant neoplasms and is therefore one of the 10 most frequent cancer diagnoses in man. Patients with CUP present with metastatic disease ...
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The ESMO guideline strategy: An identity statement and reflections on improvement
(2015)Guidelines should provide recommendations on the optimal management of a patient in specific clinical circumstances based on the scientific evidence. ESMO, as Europe's leading society in medical oncology produces a range ...
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Essential drugs for cancer chemotherapy
(1994)The WHO recommendation on essential drugs for cancer chemotherapy has been updated. General principles on the proper role of cancer chemotherapeutic agents in relation to efficacy and on the classification of tumours with ...
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Exploring the nano-surface of collagenous and other fibrotic tissues with AFM
(2017)Atomic force microscope (AFM) is a powerful and invaluable tool for imaging and probing the mechanical properties of biological samples at the nanometric scale. The importance of nano-scale characterization and nanomechanics ...
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Exploring the nano-surface of collagenous and other fibrotic tissues with AFM
(2017)Atomic force microscope (AFM) is a powerful and invaluable tool for imaging and probing the mechanical properties of biological samples at the nanometric scale. The importance of nano-scale characterization and nanomechanics ...
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Heterogeneity in cancer guidelines: Should we eradicate or tolerate?
(2008)Background: Heterogeneity in aspects of development, structure and context of oncology guidelines was not evaluated. We analysed and critically examined its implications. Materials and methods: Nine cancer clinical practice ...
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Doctoral Thesis Open Access
In vitro investigation of the role of Ras Suppressor-1 (RSU-1) and Integrin-Linked kinase (ILK) in glioma progression and invasion
(Πανεπιστήμιο Κύπρου, Πολυτεχνική Σχολή / University of Cyprus, Faculty of Engineering, 2019-12)Το πολύμορφο γλοιοβλάστωμα (Glioblastoma multiforme-GBM) είναι ο πιο επιθετικός τύπος καρκίνου του εγκεφάλου λόγω της ικανότητας των κυττάρων του να διεισδύουν σε γειτονικούς ιστούς. H μέση επιβίωση για τους ασθενείς είναι ...
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Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity
(2012)The ASCT2 transport system catalyses a sodium-dependent antiport of glutamine and other neutral amino acids which is involved in amino acid metabolism. A library of 1,2,3-dithiazoles was designed, synthesized and evaluated ...