Browsing by Subject "Cancer risk"

Article

Axillary nodal metastases from carcinoma of unknown primary (CUPAx): A systematic review of published evidence

Pentheroudakis, George; Lazaridis, G.; Pavlidis, Nicholas (2010)

Axillary lymph node metastases from adenocarcinoma or poorly differentiated carcinoma of unknown primary (CUPAx) represent a rare clinical entity without consensus on its biology, management and outcome. We systematically ...

Article

Bisphosphonate use and risk of colorectal cancer: A systematic review and meta-analysis

Bonovas, Stefanos; Nikolopoulos, Georgios K.; Bagos, Pantelis G. (2013)

Aim: A growing body of evidence suggests that bisphosphonates may have chemopreventive potential against colorectal cancer. Our aim was to examine this association through a meta-analysis of observational studies. Methods: ...

Article

Can statin therapy reduce the risk of melanoma? A meta-analysis of randomized controlled trials

Bonovas, Stefanos; Nikolopoulos, Georgios K.; Filioussi, K.; Peponi, Evangelia; Bagos, Pantelis G.; Sitaras, N. M. (2010)

A growing body of literature suggests that statins may have a chemopreventive potential against melanoma through pleiotropic anti-inflammatory, immunomodulatory, and antiangiogenesis mechanisms. Our aim was to examine this ...

Article

Cancer and pregnancy

Pavlidis, Nicholas (2000)

Article

Cancer specific risk in multiple sclerosis patients

Kyritsis, A. P.; Boussios, Stergios; Pavlidis, Nicholas (2016)

Multiple sclerosis (MS) is a chronic central nervous system (CNS) autoimmune disease. Studies of cancer risk in MS patients have shown inconsistent findings. A pubmed search of the literature on cancer risk in patients ...

Article

Chemotherapy for patients with two favourable subsets of unknown primary carcinoma: Active, but how effective?

Pentheroudakis, George; Briassoulis, E. Ch; Karavasilis, V.; Fountzilas, George; Xeros, N.; Samelis, G.; Samantas, E.; Pavlidis, Nicholas (2005)

Carcinoma of unknown primary (CUP) is characterized by dismal patient survival. The outcome of patients with two favourable risk CUP subsets was studied. Eighty patients diagnosed with either midline lymph node metastases ...

Article

Colorectal cancer screening awareness in European primary care

Mauri, D.; Pentheroudakis, George; Milousis, A.; Xilomenos, A.; Panagoulopoulou, E.; Bristianou, M.; Zacharias, G.; Christidis, D.; Mustou, E. A.; Gkinosati, A.; Pavlidis, Nicholas (2006)

Background: Adjustment for stage at diagnosis markedly reduces USA versus European colorectal cancer survival differences and a screening bias was therefore suspected. Moreover, little is known about colorectal cancer ...

Article

Commentary on pravastatin and cancer: Need for individual patient data meta-analyses

Bonovas, Stefanos; Nikolopoulos, Georgios K.; Sitaras, N. M. (2010)

Article

Depression in cancer: The many biobehavioral pathways driving tumor progression

Bortolato, B.; Hyphantis, T.; Valpione, S.; Perini, G.; Maes, M.; Morris, G.; Kubera, M.; Köhler, C. A.; Fernandes, B. S.; Stubbs, B.; Pavlidis, Nicholas; Carvalho, A. F. (2017)

Major Depressive Disorder (MDD) is common among cancer patients, with prevalence rates up to four-times higher than the general population. Depression confers worse outcomes, including non-adherence to treatment and increased ...

Article

Developing the evidence base for cancer chemoprevention: Use of meta-analysis

Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Bonovas, Stefanos (2011)

Meta-analysis is a quantitative approach for systematically combining the results of previous studies in order to arrive at conclusions about the body of research. It answers a specific research question, includes an ...

Article

ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of cancers of unknown primary site (CUP)

Briassoulis, E. Ch; Ch, F. Tolis; Bergh, Jonas; Pavlidis, Nicholas (2005)

Article

ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of cancers of unknown primary site (CUP)

Briassoulis, E. Ch; Ch, F. Tolis; Pavlidis, Nicholas (2001)

Article

ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of invasive bladder cancer

Kataja, V. V.; Pavlidis, Nicholas (2005)

Article

ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of malignant glioma

Stupp, Roger; Pavlidis, Nicholas; Jelic, S. (2005)

Article

ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of non-small-cell lung cancer (NSCLC)

Felip, E.; Stahel, R. A.; Pavlidis, Nicholas (2005)

Article

ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC)

Felip, E.; Pavlidis, Nicholas; Stahel, R. A. (2005)

Article

ESMO minimum clinical recommendations for diagnosis, treatment and follow-up pancreatic cancer

Herrmann, R.; Jost, Lorenz M.; Pavlidis, Nicholas (2005)

Article

Gene expression of estrogen receptor, progesterone receptor and microtubule-associated protein Tau in high-risk early breast cancer: A quest for molecular predictors of treatment benefit in the context of a Hellenic Cooperative Oncology Group trial

Pentheroudakis, George; Kalogeras, K. T.; Wirtz, R. M.; Grimani, I.; Zografos, G.; Gogas, H.; Stropp, U.; Pectasides, Dimitrios; Skarlos, Dimosthenis V.; Hennig, G.; Samantas, E.; Bafaloukos, Dimitrios; Papakostas, P.; Kalofonos, H. P.; Pavlidis, Nicholas; Fountzilas, George (2009)

Background Estrogen receptor (ER) and progesterone receptor (PgR) protein expression carry weak prognostic and moderate predictive utility for the outcome of early breast cancer patients on adjuvant chemohormonotherapy. ...

Article

Improved outcome of high-risk early HER2 positive breast cancer with high CXCL13-CXCR5 messenger RNA expression

Razi, E. D.; Kalogeras, K. T.; Kotoula, V.; Eleftheraki, A. G.; Nikitas, N.; Kronenwett, R.; Timotheadou, E.; Christodoulou, C.; Pectasides, Dimitrios; Gogas, H.; Wirtz, R. M.; Makatsoris, T.; Bafaloukos, Dimitrios; Aravantinos, Gerasimos; Televantou, D.; Pavlidis, Nicholas; Fountzilas, George (2012)

Background: Chemokines are important in cell migration and are thought to play a key role in metastasis. We explored the prognostic significance of C-X-C ligand-motif (CXCL) 12, CXCL13, and receptor (CXCR) 5 on disease-free ...

Article

Intracellular signalling via the AKT axis and downstream effectors is active and prognostically significant in cancer of unknown primary (CUP): A study of 100 CUP cases

Golfinopoulos, Vassilis; Pentheroudakis, George; Goussia, Anna; Siozopoulou, V.; Bobos, M.; Krikelis, D.; Cervantes, A.; Ciuleanu, T.; Marselos, M.; Fountzilas, George; Malamou-Mitsi, Vassiliki D.; Pavlidis, Nicholas (2012)

Background: Hypothesising that cancer of unknown primary (CUP) may harbour unique characteristics, we present a translational study of the immunohistochemical expression and clinical correlation of key PTEN/AKT pathway ...