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Browsing by Subject "Carcinomatous peritonitis"

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    • Article  

      Cancer of unknown primary site 

      Pavlidis, Nicholas; Pentheroudakis, George (2012)
      Cancer of unknown primary site (CUP) is a well recognised clinical disorder, accounting for 3-5 of all malignant epithelial tumours. CUP is clinically characterised as an aggressive disease with early dissemination. ...

    • Article  

      Chemotherapy for patients with two favourable subsets of unknown primary carcinoma: Active, but how effective? 

      Pentheroudakis, George; Briassoulis, E. Ch; Karavasilis, V.; Fountzilas, George; Xeros, N.; Samelis, G.; Samantas, E.; Pavlidis, Nicholas (2005)
      Carcinoma of unknown primary (CUP) is characterized by dismal patient survival. The outcome of patients with two favourable risk CUP subsets was studied. Eighty patients diagnosed with either midline lymph node metastases ...

    • Article  

      Diagnostic and therapeutic management of cancer of an unknown primary 

      Pavlidis, Nicholas; Briassoulis, E. Ch; Hainsworth, J.; Greco, F. A. (2003)
      Metastatic Cancer of Unknown Primary Site (CUP) accounts for approximately 3% of all malignant neoplasms and is therefore one of the 10 most frequent cancer diagnoses in man. Patients with CUP present with metastatic disease ...

    • Article  

      Global microRNA profiling in favorable prognosis subgroups of cancer of unknown primary (CUP) demonstrates no significant expression differences with metastases of matched known primary tumors 

      Pentheroudakis, George; Spector, Y.; Krikelis, D.; Kotoula, V.; Meiri, E.; Malamou-Mitsi, Vassiliki D.; Fountzilas, George; Sanden, M.; Pavlidis, Nicholas; Benjamin, H.; Aharonov, R. (2013)
      No data exist on biologic differences between Cancer of unknown primary (CUP) and metastatic solid tumors of known primary site. We assigned a primary tissue of origin in 40 favorable CUP patients (A: serous peritoneal ...

    • Article  

      Intracellular signalling via the AKT axis and downstream effectors is active and prognostically significant in cancer of unknown primary (CUP): A study of 100 CUP cases 

      Golfinopoulos, Vassilis; Pentheroudakis, George; Goussia, Anna; Siozopoulou, V.; Bobos, M.; Krikelis, D.; Cervantes, A.; Ciuleanu, T.; Marselos, M.; Fountzilas, George; Malamou-Mitsi, Vassiliki D.; Pavlidis, Nicholas (2012)
      Background: Hypothesising that cancer of unknown primary (CUP) may harbour unique characteristics, we present a translational study of the immunohistochemical expression and clinical correlation of key PTEN/AKT pathway ...

    • Article  

      Probing the unknown in cancer of unknown primary: Which way is the right way? 

      Pentheroudakis, George; Pavlidis, Nicholas (2010)

    • Article  

      Prognostic significance of WNT and hedgehog pathway activation markers in cancer of unknown primary 

      Fotopoulos, George; Goussia, Anna; Bareta, E.; Koumpis, E.; Chrisafi, S.; Bobos, M.; Malamou-Mitsi, Vassiliki D.; Fountzilas, George; Pavlidis, Nicholas; Pentheroudakis, George (2015)
      Background: Cancer of unknown primary (CUP) possesses distinct biology and peculiar natural history, in which the roles of the winged and hedgehog signalling pathways are unclear. Materials and methods: We constructed ...

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