Browsing by Subject "Chromosomes"
Now showing items 1-11 of 11
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Conference Object
Artificial neural networks for non-invasive chromosomal abnormality screening of fetuses
(2010)A large number of different neural network structures have been constructed, trained and tested to a large data base of pregnant women characteristics, aiming at generating a classifier-predictor for the presence of ...
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Conference Object
Artificial neural networks to investigate the significance of PAPPA and b-hCG for the prediction of chromosomal abnormalities
(2011)A systematic approach has been done, to investigate different neural network structures for the appraisal of the significance of the free b-human chorionic gonadotrophin (b-hCG) and the pregnancy associated plasma protein-A ...
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Article
Balanced translocations for the analysis of imprinted regions of the mouse genome.
(2001)Experimental studies that investigate the functional and mechanistic properties of an imprinted locus require material in which the two parental chromosome homologs can be easily distinguished. The use of animals with ...
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Article
Delta-like and Gtl2 are reciprocally expressed differentially methylated linked imprinted genes on mouse chromosome 12
(2000)The distal portion of mouse chromosome 12 is imprinted. To date, however, Gtl2 is the only imprinted gene identified on chromosome 12. Gtl2 encodes multiple alternatively spliced transcripts with no apparent open reading ...
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Article
Evaluation of the prognostic role of centromere 17 gain and HER2/topoisomerase II alpha gene status and protein expression in patients with breast cancer treated with anthracycline-containing adjuvant chemotherapy: Pooled analysis of two Hellenic Cooperative Oncology Group (HeCOG) phase III trials
(2013)Background: The HER2 gene has been established as a valid biological marker for the treatment of breast cancer patients with trastuzumab and probably other agents, such as paclitaxel and anthracyclines. The TOP2A gene has ...
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Conference Object
First trimester diagnosis of trisomy-21 using artificial neural networks
(2010)Langdon Down in 1866 reported on a syndrome in which individuals have skin appearing to be too large for the body, a nose small and a flat face. This is a chromosomal disorder caused by the presence of all or part of an ...
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Article
First Trimester Noninvasive Prenatal Diagnosis: A Computational Intelligence Approach
(2016)The objective of this study is to examine the potential value of using machine learning techniques such as artificial neural network (ANN) schemes for the noninvasive estimation, at 11-13 weeks of gestation, the risk for ...
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Conference Object
Modeling change of haplotype distributions in random mating populations using random sets
(2004)Several mathematical models have been developed to describe the genetic structure of populations. Most of these models focus on only one, or few genetic loci. In this paper, we develop a model to describe a large number ...
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Conference Object
Non-invasive trisomy 21 diagnosis using fuzzy cognitive maps
(Springer Verlag, 2016)A fuzzy Diagnostic Decision Support System (DDSS) has been developed, exploiting the possibilities of a specific algorithm which transforms a crisp dataset into fuzzy. The purpose of the developed fuzzy DDSS is the diagnosis ...
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Conference Object
Prenatal diagnosis of aneuploidy using artificial neural networks in relation to health economics
(Springer Verlag, 2016)The early detection of fetal chromosomal abnormalities such as aneuploidies, has been an important subject in medicine over the last thirty years. A pregnant woman is advised by the doctor to perform an amniocentesis test, ...
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Article
Prognostic significance of the deleted in colorectal cancer gene protein expression in high-risk resected gastric carcinoma
(2003)The deleted in colorectal cancer (DCC) gene is a candidate tumor suppressor gene that may be associated with differentiation and proliferation of normal cells. Loss of heterozygosity (LOH) of 18q, where the gene is located, ...