Browsing by Subject "Clinical use"

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    • Article  

      Cationic nanoparticles have superior transvascular flux into solid tumors: Insights from a mathematical model 

      Stylianopoulos, T.; Soteriou, K.; Fukumura, D.; Jain, R. K. (2013)
      Despite their great promise, only a few nanoparticle formulations have been approved for clinical use in oncology. The failure of nano-scale drugs to enhance cancer therapy is in large part due to inefficient delivery. To ...
    • Conference Object  

      Design rules for cancer nanomedicines 

      Stylianopoulos, T.; Soteriou, K.; Fukumura, D.; Jain, R. K. (Affiliation: Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, CyprusAffiliation: Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United StatesCorrespondence Address: Stylianopoulos, T.Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus, 2012)
      The use of nanotechnology has offered new hope for cancer detection, prevention and treatment. Nanoparticle formulations are advantageous over conventional chemotherapy because they can incorporate multiple diagnostic and ...