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Browsing by Subject "Comorbidity"

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    • Article  

      Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism and circulating ACE levels are not associated with outcome in critically ill septic patients 

      Tsantes, Argirio E.; Tsangaris, I.; Kopterides, Petros; Nikolopoulos, Georgios K.; Kalamara, Eleni; Antonakos, Georgios; Kapsimali, Violetta; Gialeraki, Argiri; Dimopoulou, Ioanna; Orfanos, S.; Dima, Kleanthi; Travlou, Anthi S.; Armaganidis, Apostolos (2012)
      Background: In critically ill patients independent studies have shown contradictory findings regarding the prognostic significance of the D/D genotype of the I/D angiotensin converting enzyme (ACE) polymorphism. The study ...

    • Article  

      Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme 

      Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)
      Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...

    • Article  

      The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis 

      Tsantes, Argirio E.; Tsangaris, I.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Kopterides, Petros; Antonakos, Georgios; Dimopoulou, Ioanna; Vrioni, G.; Kapsimali, Violetta; Dima, Kleanthi; Armaganidis, Apostolos; Travlou, Anthi S. (2010)
      Background. There is considerable evidence that elevated plasma homocysteine levels are associated with a prothrombotic milieu, whereas activation of the coagulation cascade is an important component of the pathogenesis ...

    • Article  

      Evaluation of thermal discomfort in Athens territory and its effect on the daily number of recorded patients at hospitals' emergency rooms 

      Pantavou, K. G.; Theoharatos, G.; Nikolopoulos, Georgios K.; Katavoutas, G.; Asimakopoulos, D. (2008)
      Previous research has shown that temperature and humidity affect human health. However, only a few studies have examined the association of a biometeorological index, which combines several meteorological parameters and ...

    • Article  

      HIV-1 outbreak among injecting drug users in Greece, 2011: A preliminary report 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Paraskeva, D.; Antoniadou, Anastasia; Lazanas, Marios; Gargalianos, Panagiotis; Psychogiou, M.; Malliori-Minerva, Melpomeni; Kremastinou, Jenny; Hatzakis, A. (2011)
      A significant increase (more than 10-fold) in the number of newly diagnosed HIV-1 infections among injecting drug users (IDUs) was observed in Greece during the first seven months of 2011. Molecular epidemiology results ...

    • Article  

      HIV/HBV co-infection and rate of antiretroviral treatment change after highly active antiretroviral treatment initiation in a cohort of HIV-infected patients in Greece 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2010)
      The current study investigated the impact of human immunodeficiency virus (HIV)/hepatitis B virus (HBV) co-infection on the rate of change of antiretroviral drugs after the initiation of highly active antiretroviral treatment ...

    • Article  

      Maltreatment Profiles Among Incarcerated Boys With Callous-Unemotional Traits 

      Kimonis, Eva R.; Fanti, Kostas A.; Isoma, Zachary; Donoghue, Kathleen (2013)
      Callous-unemotional (CU) traits in youth are believed to be a developmental precursor to adult psychopathy, tapping its affective dimension. There is growing support for the existence of variants of psychopathy that can ...

    • Article  

      Palliative chemotherapy in elderly patients with common metastatic malignancies: A Hellenic Cooperative Oncology Group registry analysis of management, outcome and clinical benefit predictors 

      Pentheroudakis, George; Fountzilas, George; Kalofonos, H. P.; Golfinopoulos, Vassilis; Aravantinos, Gerasimos; Bafaloukos, Dimitrios; Papakostas, P.; Pectasides, Dimitrios; Christodoulou, C.; Syrigos, K.; Economopoulos, T.; Pavlidis, Nicholas (2008)
      Introduction: Cancer in the elderly is a common health issue in developed societies. We sought to present epidemiology, management and outcome data on fit elderly patients with common metastatic cancers and to identify ...

    • Article  

      Psychosocial predictors of health outcomes in colorectal cancer: A comprehensive review 

      Sales, P. M. G.; Carvalho, A. F.; McIntyre, R. S.; Pavlidis, Nicholas; Hyphantis, T. (2014)
      Background: A diagnosis of colorectal cancer (CRC) and its long-term treatment may lead to significant psychological distress and impaired health-related quality of life (HRQoL) for a significant proportion of patients. ...

    • Article  

      A Rare Coexistence of Retroperitoneal Pararenal Castleman's Disease with Focal Nodular Hyperplasia 

      Theodosopoulos, Theodosios; Karakatsanis, A.; Yiallourou, Anneza I.; Nikolakopoulos, Fotios; Psychogiou, Vassiliki; Karvouni, Helen; Voros, Dionysios (2013)
      Castleman's disease is a distinct form of lymph node hyperplasia divided into a solitary and a multicentric type. The solitary type occurs most commonly in the mediastinum and is usually asymptomatic. We present a patient ...

    • Article  

      Risk factors affecting the incidence of infection after orthopaedic surgery: The role of chemoprophylaxis 

      Masgala, Aikaterini; Chronopoulos, Efstathios; Nikolopoulos, Georgios K.; Sourlas, J.; Lallos, Stergios; Brilakis, Emmanuel; Lazarettos, John; Efstathopoulos, Nikolaos (2012)
      The incidence of surgical site infection and urinary tract infection following orthopaedic procedures has diminished in recent years due to modern antimicrobial prophylaxis. We conducted a case-control study (100 cases, ...

    • Article  

      Somatization is associated with physical health-related quality of life independent of anxiety and depression in cancer, glaucoma and rheumatological disorders 

      Hyphantis, T.; Tomenson, B.; Paika, V.; Almyroudi, A.; Pappa, C.; Tsifetaki, N.; Voulgari, P. V.; Drosos, Alexandros A.; Pavlidis, Nicholas; Creed, F. (2009)
      Purpose: To test the relative importance of anxiety, depression and somatization as correlates of physical health-related quality of life (HRQOL) in several chronic physical disorders. Methods: In a cross-sectional study ...

    • Article  

      Trabectedin-related rhabdomyolysis: An uncommon but fatal toxicity 

      Stoyianni, A.; Kapodistrias, N.; Kampletsas, E. O.; Pentheroudakis, George; Pavlidis, Nicholas (2011)
      Rhabdomyolysis is defined as the dissolution of striped muscle characterized by the leakage of intracellular muscle components into the circulation, which can ultimately lead to renal failure with a possible fatal outcome. ...

    • Article  

      Treatment of colorectal cancer in the elderly: A review of the literature 

      Golfinopoulos, Vassilis; Pentheroudakis, George; Pavlidis, Nicholas (2006)
      Although major progress has been achieved in the treatment of colorectal cancer, there are still several questions open for discussion concerning the management of elderly colorectal cancer patients. We conducted a review ...

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