• Article  

      Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism and circulating ACE levels are not associated with outcome in critically ill septic patients 

      Tsantes, Argirio E.; Tsangaris, I.; Kopterides, Petros; Nikolopoulos, Georgios K.; Kalamara, Eleni; Antonakos, Georgios; Kapsimali, Violetta; Gialeraki, Argiri; Dimopoulou, Ioanna; Orfanos, S.; Dima, Kleanthi; Travlou, Anthi S.; Armaganidis, Apostolos (2012)
      Background: In critically ill patients independent studies have shown contradictory findings regarding the prognostic significance of the D/D genotype of the I/D angiotensin converting enzyme (ACE) polymorphism. The study ...
    • Article  

      The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis 

      Tsantes, Argirio E.; Tsangaris, I.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Kopterides, Petros; Antonakos, Georgios; Dimopoulou, Ioanna; Vrioni, G.; Kapsimali, Violetta; Dima, Kleanthi; Armaganidis, Apostolos; Travlou, Anthi S. (2010)
      Background. There is considerable evidence that elevated plasma homocysteine levels are associated with a prothrombotic milieu, whereas activation of the coagulation cascade is an important component of the pathogenesis ...
    • Article  

      Is the mortality rate for septic shock really decreasing? 

      Christaki, Eirini; Opal, Steven M. (2008)
      Survival rates for patients in septic shock have gradually improved in critical care units worldwide over the last 25 years. Further improvement will be predicated on the discovery of new therapies to disrupt the underlying ...