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Browsing by Subject "Cytoskeletal Proteins"

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    • Article  

      Discovery of old diseases: The molecular approach [1] 

      Constantinou-Deltas, Constantinos D. (2003)

    • Article  

      Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes 

      Markstein, M.; Pitsouli, Chrysoula; Villalta, C.; Celniker, S. E.; Perrimon, N. (2008)
      A major obstacle to creating precisely expressed transgenes lies in the epigenetic effects of the host chromatin that surrounds them. Here we present a strategy to overcome this problem, employing a Gal4-inducible luciferase ...

    • Article  

      Familial Mediterranean fever associated pyrin mutations in Greece 

      Print Email Konstantopoulos, Konstantinos; Kanta, Alexandra; Constantinou-Deltas, Constantinos D.; Atamian, V.; Mavrogianni, D.; Tzioufas, A. G.; Kollainis, I.; Ritis, K.; Moutsopoulos, H. M. (2003)
      Objective: To search for pyrin mutations associated with familial Mediterranean fever (FMF) in Greece. Patients and methods: 62 patients fulfilling the Tel Hashomer diagnostic criteria for definite (33) or probable (29) ...

    • Article  

      Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy 

      Kirmizis, Antonis; Bartley, S. M.; Farnham, P. J. (2003)
      We have previously identified SU(Z)12 as an E2F target gene. Because many E2F target genes encode proteins that are critical for the control of cell proliferation, we have further characterized the regulation and expression ...

    • Article  

      Multiplex molecular diagnosis of MEFV mutations in patients with Familial Mediterranean fever by light-cycler real-time PCR 

      Rossou, Elena; Kouvatsi, Anastasia; Aslanidis, Charalampos; Constantinou-Deltas, Constantinos D. (2005)

    • Article  

      Non-isotopic RNase cleavage assay for mutation detection in MEFV, the gene responsible for familial Mediterranean fever, in a cohort of Greek patients 

      Ritis, K.; Giaglis, Stavros; Spathari, N.; Micheli, A.; Zonios, D.; Tzoanopoulos, D.; Constantinou-Deltas, Constantinos D.; Rafail, S.; Mean, R.; Papadopoulos, Vassilios P.; Tzioufas, A. G.; Moutsopoulos, H. M.; Kartalis, G. (2004)
      Background: The MEFV gene is responsible for familial Mediterranean fever (FMF). Several disease associated mutations have been identified. The range of genetic variation in MEFV in Greek patients has not been determined. ...

    • Article  

      Vasodilator-Stimulated Phosphoprotein (VASP) depletion from breast cancer MDA-MB-231 cells inhibits tumor spheroid invasion through downregulation of Migfilin, β-catenin and urokinase-plasminogen activator (uPA) 

      Gkretsi, V.; Stylianou, A.; Stylianopoulos, T. (2017)
      A hallmark of cancer cells is their ability to invade surrounding tissues and form metastases. Cell-extracellular matrix (ECM)-adhesion proteins are crucial in metastasis, connecting tumor ECM with actin cytoskeleton thus ...

    • Doctoral Thesis  Open Access

      Ταυτοποίηση και λειτουργικός χαρακτηρισμός μιας νέας πρωτεϊνης τύπου Κατανίνης, KATNAL2, σε κύτταρα ποντικού 

      Βερβέρης, Αντώνης Π. (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2015-05)
      Η Katanin αποτελεί μία φυλογενετικά ευρέως διαδεδομένη και καλά χαρακτηρισμένη πρωτεΐνη που ταξινομείται στην υπεροικογένεια των ΑΑΑ ATPάσων και χαρακτηρίζεται από τη δράση της ως ένζυμο κατάτμησης των μικροσωληνίσκων, ...

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