Browsing by Subject "DNA methylation"
Now showing items 1-5 of 5
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Cross-talk among epigenetic modifications: Lessons from histone arginine methylation
(2013)Epigenetic modifications, including those occurring on DNA and on histone proteins, control gene expression by establishing and maintaining different chromatin states. In recent years, it has become apparent that epigenetic ...
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First Trimester Noninvasive Prenatal Diagnosis: A Computational Intelligence Approach
(2016)The objective of this study is to examine the potential value of using machine learning techniques such as artificial neural network (ANN) schemes for the noninvasive estimation, at 11-13 weeks of gestation, the risk for ...
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MeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21
(2012)Objective: To reevaluate the efficiency of the 12 differentially methylated regions (DMRs) used in the methylated DNA immunoprecipitation (MeDIP) real-time quantitative polymerase chain reaction (real-time qPCR) based ...
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A new non-invasive prenatal diagnosis of Down syndrome through epigenetic markers and real-time qPCR
(2012)Introduction: Non-invasive prenatal diagnosis (NIPD) of Down syndrome is rapidly evolving. Currently, two applications for NIPD of Down syndrome have been developed with potential and have displayed positive results