• Book Chapter  

      Breast Cancer Epigenetics 

      Pitta, Chara A.; Constantinou, Andreas I. (Elsevier Inc., 2015)
      The molecular mechanisms underlying the development and progression of breast cancer are far from being understood. It is obvious that the initiation of breast cancer as well as its transition toward distinct breast cancer ...
    • Article  

      Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance 

      Pitta, Chara A.; Papageorgis, P.; Charalambous, Christina; Constantinou, Andreas I. (2013)
      The purpose of this work is to determine the molecular mechanisms underlying tamoxifen resistance. We show here that ER-β is epigenetically silenced in a cell line with acquired tamoxifen resistance (MCF-7/TAM-R) and this ...