Browsing by Subject "Depression"

Article

Antiretrovirals for HIV exposure prophylaxis

Nikolopoulos, Georgios K.; Tsiodras, Sotirios; Bonovas, Stefanos; Hatzakis, A. (2012)

Infection with Human Immunodeficiency Virus (HIV) remains a global public health problem. Although the epidemic has not been completely controlled, there was considerable progress in HIV prevention and treatment during the ...

Article

Anxiety, depression and defense mechanisms associated with treatment decisional preferences and quality of life in non-metastatic breast cancer: A 1-year prospective study

Hyphantis, T.; Almyroudi, A.; Paika, V.; Degner, L. F.; Carvalho, A. F.; Pavlidis, Nicholas (2013)

Objective: Treatment decisional preferences impact breast cancer patients' health-related quality of life (HRQoL) and may relate to psychological variables, although many aspects of this relationship remain unknown. This ...

Article

The association of community violence exposure with middle-school achievement: A prospective study

Henrich, Christopher C.; Schwab-Stone, M.; Fanti, Kostas A.; Jones, S. M.; Ruchkin, V. (2004)

This study investigated the long-term effects of exposure to community violence on academic achievement and feelings of safety in school among a large sample of urban middle-school students (N = 759). It also considered ...

Article

A Biophysical Model of Endocannabinoid-Mediated Short Term Depression in Hippocampal Inhibition

Zachariou, Margarita; Alexander, S. P. H.; Coombes, S.; Christodoulou, Chris C. (2013)

Memories are believed to be represented in the synaptic pathways of vastly interconnected networks of neurons. The plasticity of synapses, that is, their strengthening and weakening depending on neuronal activity, is ...

Article

Does psychological distress vary between younger and older adults in health and disease?

Goulia, P.; Papadimitriou, I.; Machado, M. O.; Mantas, C.; Pappa, C.; Tsianos, Epameinondas; Pavlidis, Nicholas; Drosos, Alexandros A.; Carvalho, A. F.; Hyphantis, T. (2012)

Objective: The effect of age on psychological distress remains controversial and it is unclear how a chronic medical illness influences this association. We aimed to compare the level of psychological distress between ...

Article

«Juvenile» oncology - A missing subspecialty. The experience of a reference cancer centre

Pentheroudakis, George; Mauri, D.; Kostadima, Lida; Golfinopoulos, Vassilis; Alexiou, G.; Karakatsanis, A.; Pavlidis, Nicholas (2006)

Introduction: Despite unique tumor epidemiology and a higher cancer incidence compared to pediatric patients, adolescents and young adults have not been receiving specialized, multidisciplinary, centralized care. In an ...

Article

Liens entre le développement de la pleine conscience et l’amélioration de la dépression et de l’anxiété

Grignon, Clémence; Zachariou, Zacharias; Lascar, Philippe; Bouvet, Cyrille (2015)

Résumé Dernièrement, de nombreuses études se sont intéressées à la notion de pleine conscience, incluse dans la troisième vague des thérapies comportementales et cognitives. Notre objectif est de déterminer l’existence de ...

Article

Major depressive disorder in breast cancer: A critical systematic review of pharmacological and psychotherapeutic clinical trials

Carvalho, A. F.; Hyphantis, T.; Sales, P. M. G.; Soeiro-de-Souza, M. G.; Macêdo, D. S.; Cha, D. S.; McIntyre, R. S.; Pavlidis, Nicholas (2014)

Background: While women with breast cancer often face varying levels of psychological distress, there is a subgroup whose symptomatology reaches a threshold for diagnosis of major depressive disorder (MDD). Major depressive ...

Article

Multicenter phase-II trial of irinotecan plus oxaliplatin [IROX regimen] in patients with poor-prognosis cancer of unknown primary: A hellenic cooperative oncology group study

Briassoulis, E. Ch; Fountzilas, George; Bamias, A. T.; Dimopoulos, M. A.; Xiros, N.; Aravantinos, Gerasimos; Samantas, E.; Kalofonos, H. P.; Makatsoris, T.; Mylonakis, N.; Papakostas, P.; Skarlos, Dimosthenis V.; Varthalitis, I.; Pavlidis, Nicholas (2008)

Background: Cancer of unknown primary (CUP) lacks established therapy although it affects 3% of cancer patients. We evaluated the irinotecan- oxaliplatin combination (IROX regimen) in previously untreated patients with ...

Article

Perceived social support helps, but does not buffer the negative impact of anxiety disorders on quality of life and perceived stress

Panayiotou, Georgia; Karekla, Maria (2013)

Purpose: Anxiety disorders are prevalent and substantially hinder quality of life, in all domains, including social connections, mental and physical health. Past research on stress indicates that perceived social support ...

Article

Personality factors associated with psychological distress in testicular cancer survivors

Siafaka, V.; Hyphantis, T.; Alamanos, Y. P.; Fountzilas, George; Skarlos, Dimosthenis V.; Pectasides, Dimitrios; Mavreas, V.; Pavlidis, Nicholas (2008)

The aim of this study was to investigate symptoms of anxiety and depression in testicular cancer survivors (TCSs) and to identify personality traits associated with psychological distress in these patients by means of the ...

Article

Personality variables as predictors of early non-metastatic colorectal cancer patients' psychological distress and health-related quality of life: A one-year prospective study

Hyphantis, T.; Paika, V.; Almyroudi, A.; Kampletsas, E. O.; Pavlidis, Nicholas (2011)

Objective: We aimed to assess the course of early non-metastatic colorectal cancer patients' psychological distress and health-related quality of life (HRQOL) and to identify relevant clinical and psychological predictors ...

Article

Psychiatric manifestations, personality traits and health-related quality of life in cancer of unknown primary site

Hyphantis, T.; Papadimitriou, I.; Petrakis, Dimitrios; Fountzilas, George; Repana, D.; Assimakopoulos, K.; Carvalho, A. F.; Pavlidis, Nicholas (2013)

Objective Psychiatric manifestations and personality traits are known to influence cancer patients. We aimed to assess psychological distress symptoms, psychosocial factors and health-related quality of life (HRQoL) in ...

Article

Psychosocial predictors of health outcomes in colorectal cancer: A comprehensive review

Sales, P. M. G.; Carvalho, A. F.; McIntyre, R. S.; Pavlidis, Nicholas; Hyphantis, T. (2014)

Background: A diagnosis of colorectal cancer (CRC) and its long-term treatment may lead to significant psychological distress and impaired health-related quality of life (HRQoL) for a significant proportion of patients. ...

Article

Radiopharmaceuticals in neurological and psychiatric disorders

Valotassiou, Varvara; Wozniak, Greta; Sifakis, N.; Demakopoulos, Nikolaos; Georgoulias, Panagiotis (2008)

The development of functional brain nuclear medicine techniques and their application in the investigation of neuropsychiatric disorders, have contributed significantly in the illumination of the underlying pathophysiological ...

Article

Serotonin and neuron-specific enolase: Serum acute and mid-term levels and their association with posttraumatic depression

Wozniak, Greta; Georgoulias, Panagiotis; Iliadis, Charalambos; Valotassiou, Varvara; Papadopoulos, G.; Bagiatis, Vasilis; Tsougos, Ioannis; Paterakis, K. N.; Fountas, Kostas N. (2010)

OBJECTIVES: To investigate the association between serotonin (SER), cholesterol, and neuron-specific enolase (NSE) serum levels with depression after traumatic brain injury (TBI). MATERIALS AND METHODS: Seventy-four patients ...

Article

Serotonin reuptake inhibitor antidepressants (SSRIs) against atherosclerosis

Wozniak, Greta; Toska, Aikaterini; Saridi, Maria; Mouzas, Odysseas (2011)

Selective serotonin reuptake inhibitors (SSRIs) are a class of drug widely used for treatment of mood disorders, including depression and cardiovascular disease. A search for related articles in the PubMed database was ...

Article

Somatization is associated with physical health-related quality of life independent of anxiety and depression in cancer, glaucoma and rheumatological disorders

Hyphantis, T.; Tomenson, B.; Paika, V.; Almyroudi, A.; Pappa, C.; Tsifetaki, N.; Voulgari, P. V.; Drosos, Alexandros A.; Pavlidis, Nicholas; Creed, F. (2009)

Purpose: To test the relative importance of anxiety, depression and somatization as correlates of physical health-related quality of life (HRQOL) in several chronic physical disorders. Methods: In a cross-sectional study ...

Article

Stress-based animal models of depression: Do we actually know what we are doing?

Yin, X.; Guven, Nuri; Dietis, Nikolas (2016)

Depression is one of the leading causes of disability and a significant health-concern worldwide. Much of our current understanding on the pathogenesis of depression and the pharmacology of antidepressant drugs is based ...

Article

Παράγοντες εμφάνισης καταθλιπτικής συμπτωματ..

Kyloudis, Panagiotis; Georgiadis, Michae; Rekleiti, Maria; Giaglis, George; Wozniak, Greta; Roupa, Zoe (2011)

Depression is one of the most common psychiatric illnesses nowadays and according to the World Health Organization (WHO) it affects millions of people worldwide. It is an illness that has multiple causes, and it is the ...