Browsing by Subject "Drug discoveries"

Now showing items 1-3 of 3

    • Conference Object  

      Deriving quantitative structure-activity relationship models using genetic programming for drug discovery 

      Neophytou, K.; Nicolaou, Christos A.; Pattichis, Constantinos S.; Schizas, Christos N. (2008)
      Genetic Programming is a heuristic search algorithm inspired by evolutionary techniques that has been shown to produce satisfactory solutions to problems related to several scientific domains [1]. Presented here is a ...
    • Article  

      Digital magnetic tagging for multiplexed suspension-based biochemical assays 

      Mitrelias, Thanos; Trypiniotis, Theodossis; Palfreyman, J. J.; Hong, B.; Vyas, K.; Hayward, T. J.; Llandro, J.; Kopper, K. P.; Bland, J. A. C.; Robertson, P. A.; Barnes, C. H. W. (2009)
      Microarrays and suspension (or bead)-based technologies have attracted significant interest for their broad applications in high throughput molecular biology. However, the throughput of microarrays will always be limited ...
    • Article  

      De novo drug design using multiobjective evolutionary graphs 

      Nicolaou, Christos A.; Apostolakis, Joannis; Pattichis, Constantinos S. (2009)
      Drug discovery and development is a complex, lengthy process, and failure of a candidate molecule can occur as a result of a combination of reasons, such as poor pharmacokinetics, lack of efficacy, or toxicity. Successful ...