• Article  

      Interaction of metal complexes with G-quadruplex DNA 

      Georgiades, Savvas N.; Abd Karim, N. H.; Suntharalingam, K.; Vilar, R. (2010)
      [Figure Presented] Guanine-rich sequences of DNA can assemble into tetrastranded structures known as G-quadruplexes. It has been suggested that these secondary DNA structures could be involved in the regulation of several ...
    • Article  

      Interaction pharmacokinetis of pegylated liposomal doxorubicin (Caelyx) on coadministration with paclitaxel or docetaxel 

      Briassoulis, E. Ch; Karavasilis, V.; Tzamakou, E.; Rammou, D.; Soulti, K.; Piperidou, C.; Pavlidis, Nicholas (2004)
      Purpose: To investigate the pharmacokinetics of polyethylene glycol-coated liposomal doxorubicin (PLD, Caelyx) when given as a single agent and in combination with the taxanes paclitaxel or docetaxel in humans. Methods: ...
    • Article  

      Trabectedin-related rhabdomyolysis: An uncommon but fatal toxicity 

      Stoyianni, A.; Kapodistrias, N.; Kampletsas, E. O.; Pentheroudakis, George; Pavlidis, Nicholas (2011)
      Rhabdomyolysis is defined as the dissolution of striped muscle characterized by the leakage of intracellular muscle components into the circulation, which can ultimately lead to renal failure with a possible fatal outcome. ...