Browsing by Subject "Escherichia coli"
Now showing items 1-9 of 9
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Article
Binding free energies and free energy components from molecular dynamics and Poisson-Boltzmann calculations. Application to amino acid recognition by aspartyl-tRNA synthetase
(2001)Specific amino acid binding by aminoacyl-tRNA synthetases (aaRS) is necessary for correct translation of the genetic code. Engineering a modified specificity into aminoacyl-tRNA synthetases has been proposed as a means to ...
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Article
Cefditoren: Comparative efficacy with other antimicrobials and risk factors for resistance in clinical isolates causing UTIs in outpatients
(2012)Background: To investigate a possible role of Cefditoren, a recently marketed in Greece third-generation oral cephalosporin in urinary infections of outpatients.Methods: During a multicenter survey of Enterobacteriaceae ...
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Article
Ciprofloxacin conjugated to diphenyltin(iv): a novel formulation with enhanced antimicrobial activity
(Royal Society of Chemistry, 2020-09-07)The metalloantibiotic of formula Ph2Sn(CIP)2 (CIPTIN) (HCIP = ciprofloxacin) was synthesized by reacting ciprofloxacin hydrochloride (HCIP·HCl) (an antibiotic in clinical use) with diphenyltin dichloride (Ph2SnCl2DPTD). ...
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Article
Fourier transform infrared (FTIR) and step-scan time-resolved FTIR spectroscopies reveal a unique active site in cytochrome caa3 oxidase from Thermus thermophilus
(2002)Fourier transform infrared (FTIR) and step-scan time-resolved FTIR difference spectra are reported for the [carbonmonoxy]cytochrome caa3 from Thermus thermophilus. A major C-O mode of heme a3 at 1958 cm-1 and two minor ...
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Article
Photoselected electron transfer pathways in DNA photolyase
(2007)Cyclobutane dimer photolyases are proteins that bind to UV-damaged DNA containing cyclobutane pyrimidine dimer lesions. They repair these lesions by photo-induced electron transfer. The electron donor cofactor of a photolyase ...
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Doctoral Thesis Open Access
Probing the role of rare codons in coding sequences of Escherichia coli
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2015-05)Βασικός στόχος της έρευνάς μας ήταν να ανακαλύψουμε και να περιγράψουμε το βιολογικό ρόλο της ύπαρξης των σπάνιων κωδικονίων (που ονομάζουμε Rare Codon Clusters–RCCs), χρησιμοποιώντας πλήρη στοιχεία του γονιδιώματος της ...
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Doctoral Thesis
Pseudomonas aeruginosa interactions with its host and with commensal escherichia coli
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2018–10)Το ανθρώπινο μικροβίωμα αποτελείται από μικροοργανισμούς που φιλοξενούνται σε διάφορα μέρη του ανθρώπινου σώματος. Περιοχές που έρχονται σε επαφή με το περιβάλλον ή με την καταναλωθέντα τροφή όπως, το δέρμα, το αναπνευστικό ...
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Article
Resonance Raman detection of the Fe2+-C-N modes in heme-copper oxidases: A probe of the active site
(2004)Resonance Raman spectroscopy has been employed to investigate the reduced cyano complexes of cytochrome aa3 from bovine heart and Rhodobacter sphaeroides and of cytochrome bo3 from E. coli. In the aa 3-type oxidases, the ...
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Article
Synthetic libraries of tyrosine-derived bacterial metabolites
(2008)The preparation of a collection of 131 small molecules, reminiscent of families of long chain N-acyl tyrosines, enamides and enol esters that have been isolated from heterologous expression of environmental DNA (eDNA) in ...