Browsing by Subject "Experimental"
Now showing items 1-9 of 9
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Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
(2013)Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan ...
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Cytotoxic activity of interferon-treated macrophages studied by various inhibitors
(1978)The ability of interferon-treated macrophages to kill or inhibit the growth of tumor cells is markedly influenced by the local environment. The macrophage cytotoxic effector system is regulated by serum and other environmental ...
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Effect of maleic anhydride-divinyl ether copolymers on experimental M109 metastases and macrophage tumoricidal function
(1978)Pyran copolymer (NSC-46015) was compared with five maleic anhydride-divinyl ether copolymers (MVEs) of narrow molecular weight range both for the ability to render macrophages nonspecifically tumoricidal and to retard the ...
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Macrophage activation and antitumor activity of a Brucella abortus ether extract, Bru-Pel
(1978)Bru-Pel and Brucella abortus lipopolysaccharide (LPS) were tested for both macrophage activation and antitumor activity in an artificial metastasis model. Resting macrophages were rendered nonspecifically tumoricidal for ...
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Positive urinary cytology in patients with lung cancer in the absence of obvious urine tract metastases
(2011)Purpose: To study the phenomenon of positive urine cytology in patients with lung cancer in the absence of obvious urothelial metastases. Patients and methods: 150 patients with small (SCLC) and non-small cell lung cancer ...
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Regulation of macrophage tumoricidal function: a role for prostaglandins of the E series
(1978)Exogenously added prostaglandins E1 and E2, but not F2alpha, inhibited the tumoricidal activity of interferon-activated macrophages of mice. A role for adenosine 3',5'-monophosphate (cyclic AMP) in modulating macrophage ...
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Stress-induced impairment of macrophage tumoricidal function
(1980)Several studies have shown the effect of stress on immune cells and their functions. The purpose of the present work was to investigate the influence of acute immobilization stress on macrophage nonspecific tumoricidal ...
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Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging
(2009)Intravital multiphoton microscopy has provided powerful mechanistic insights into health and disease and has become a common instrument in the modern biological laboratory. The requisite high numerical aperture and exogenous ...