Browsing by Subject "Focal Adhesion Protein-Tyrosine Kinases"
Now showing items 1-5 of 5
-
Article
Activation of endogenous FAK via expression of its amino terminal domain in xenopus embryos
(2012)Background: The Focal Adhesion Kinase is a well studied tyrosine kinase involved in a wide number of cellular processes including cell adhesion and migration. It has also been shown to play important roles during embryonic ...
-
Article
Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells
(2017)We previously identified focal adhesion kinase (FAK) as an important regulator of ciliogenesis in multiciliated cells. FAK and other focal adhesion (FA) proteins associate with the basal bodies and their striated rootlets ...
-
Article
FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis
(2014)Spindle orientation is critical for proper morphogenesis of organs and tissues as well as for the maintenance of tissue morphology. Although significant progress has been made in understanding the mechanisms linking the ...
-
Article
Imaging morphogenesis, in Xenopus with Quantum Dot nanocrystals
(2009)Mesoderm migration is a well studied morphogenetic movement that takes place during Xenopus gastrulation. The study of mesoderm migration and other morphogenetic movements has been primarily based on in vitro assays due ...
-
Article
Making the Connection: Ciliary Adhesion Complexes Anchor Basal Bodies to the Actin Cytoskeleton
(2014)Cilia have been associated with diverse developmental and physiological processes, and defects in cilia underlie a number of genetic conditions. Several lines of evidence support a critical role of the actin cytoskeleton ...