Browsing by Subject "Genetic heterogeneity"
Now showing items 1-5 of 5
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Article
Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis
(2007)The effect of the 675 insertion/deletion (4G/5G) polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene on the risk of venous thromboembolism (VTE) remains controversial. In this study, we performed a meta-analysis ...
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The GNB3 C825T polymorphism and essential hypertension: A meta-analysis of 34 studies including 14 094 cases and 17 760 controls
(2007)OBJECTIVES: The C825T single nucleotide polymorphism of the G-protein β3 (GNB3) has been implicated in susceptibility to essential hypertension, through the expression of an alternatively spliced truncated variant. In an ...
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Article
HIV epidemiology in Greece
(2008)Greece has experienced early the effect of HIV/AIDS on morbidity and mortality. The era of highly active antiretroviral therapy has alleviated many of the consequences of the epidemic, however, HIV infection remains an ...
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Article
A method for meta-analysis of case-control genetic association studies using logistic regression
(2007)We propose here a simple and robust approach for meta-analysis of molecular association studies. Making use of the binary structure of the data, and by treating the genotypes as independent variables in a logistic regression, ...
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Article
Presymptomatic molecular diagnosis of autosomal dominant polycystic kidney disease using PKD1- and PKD2-linked markers in Cypriot families
(1996)Autosomal dominant polycystic kidney disease (ADPKD), is a heterogeneous disorder, primarily characterized by the formation of cysts in the kidneys, and the late development in life of progressive chronic kidney failure. ...