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Browsing by Subject "Heart failure"

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    • Article  

      Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism and circulating ACE levels are not associated with outcome in critically ill septic patients 

      Tsantes, Argirio E.; Tsangaris, I.; Kopterides, Petros; Nikolopoulos, Georgios K.; Kalamara, Eleni; Antonakos, Georgios; Kapsimali, Violetta; Gialeraki, Argiri; Dimopoulou, Ioanna; Orfanos, S.; Dima, Kleanthi; Travlou, Anthi S.; Armaganidis, Apostolos (2012)
      Background: In critically ill patients independent studies have shown contradictory findings regarding the prognostic significance of the D/D genotype of the I/D angiotensin converting enzyme (ACE) polymorphism. The study ...

    • Article  

      Dose-dense sequential adjuvant chemotherapy followed, as indicated, by trastuzumab for one year in patients with early breast cancer: First report at 5-year median follow-up of a Hellenic Cooperative Oncology Group randomized phase III trial 

      Fountzilas, George; Dafni, U.; Papadimitriou, C.; Timotheadou, E.; Gogas, H.; Eleftheraki, A. G.; Xanthakis, I.; Christodoulou, C.; Koutras, A. K.; Papandreou, C. N.; Papakostas, P.; Miliaras, S.; Markopoulos, C.; Dimitrakakis, C.; Korantzopoulos, Panagiotis; Karanikiotis, C.; Bafaloukos, Dimitrios; Kosmidis, Paraskevas A.; Samantas, E.; Varthalitis, I.; Pavlidis, Nicholas; Pectasides, Dimitrios; Dimopoulos, M. A. (2014)
      Background: Dose-dense sequential chemotherapy including anthracyclines and taxanes has been established in the adjuvant setting of high-risk operable breast cancer. However, the preferable taxane and optimal schedule of ...

    • Article  

      Late toxicity in survivors from adolescent cancers 

      Pentheroudakis, George; Pavlidis, Nicholas (2007)
      Nowadays three quarters of adolescents with cancer are cured but half of them experience a late toxic effect of antineoplastic therapy that interferes with their physical and psychosocial health. This review recapitulates ...

    • Article  

      Mitoxantrone: An active new agent in the treatment of advanced breast cancer 

      Stuart-Harris, R. C.; Bozek, T.; Pavlidis, Nicholas; Smith, I. E. (1984)
      Sixty-five patients with advanced breast carcinoma were treated with mitoxantrone, an anthracenedione with structural similarities to adriamycin. The series included 26 patients who had received no prior chemotherapy. ...

    • Article  

      Paclitaxel-carboplatin combination chemotherapy in advanced breast cancer: Accumulating evidence for synergy, efficacy, and safety 

      Pentheroudakis, George; Razi, E. D.; Athanasiades, A.; Pavlidis, Nicholas; Fountzilas, George (2006)
      Patients with metastatic breast cancer receive multiple lines of cytotoxic chemotherapy, with taxane and anthracycline-based regimens being the most active. Anthracyclines carry the risk of significant cardiotoxicity at ...

    • Article  

      Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis 

      Athyros, Vasilios G.; Tziomalos, Konstantinos; Gossios, Thomas D.; Griva, Theodora; Anagnostis, Panagiotis; Kargiotis, Konstantinos; Pagourelias, Efstathios D.; Theocharidou, Eleni; Karagiannis, Asterios; Mikhailidis, Dimitri P.; Basdekas, S.; Bouloukos, V.; Christaki, Eirini; Dimopoulou, S.; Hartamba, E.; Kakafika, A.; Kapousouzi, M.; Koumaras, H.; Mitsiou, E.; Papageorgiou, A.; Pehlivanidis, A.; Petridis, D.; Sekeri, Z.; Skaperdas, A.; Symeonidis, A. (2010)
      Long-term statin treatment reduces the frequency of cardiovascular events, but safety and efficacy in patients with abnormal liver tests is unclear. We assessed whether statin therapy is safe and effective for these patients ...

    • Article  

      Serotonin reuptake inhibitor antidepressants (SSRIs) against atherosclerosis 

      Wozniak, Greta; Toska, Aikaterini; Saridi, Maria; Mouzas, Odysseas (2011)
      Selective serotonin reuptake inhibitors (SSRIs) are a class of drug widely used for treatment of mood disorders, including depression and cardiovascular disease. A search for related articles in the PubMed database was ...

    • Article  

      Ultrastructural pathology of the heart in patients with beta-thalassaemia major 

      Kyriacou, Kyriacos; Michaelides, Y.; Senkus, R.; Simamonian, Krikor; Pavlidis, Nicholas; Antoniades, L.; Zambartas, C. (2000)
      Patients with beta-thalassaemia major frequently suffer from hypersiderosis which leads to hemochromatosis of major organs such as the heart and liver. Little information exists about the ultrastructural pathology of the ...

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