Browsing by Subject "Highly active antiretroviral therapy"

Article

Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme

Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)

Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...

Article

Effect of hepatitis C virus on immunological and virological responses in HIV-infected patients initiating highly active antiretroviral therapy: A meta-analysis

Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Dimou, Niki L.; Bagos, Pantelis G.; Saroglou, G.; Velonakis, E.; Hatzakis, A. (2013)

Co-infection of human immunodeficiency virus (HIV) with hepatitis C virus (HCV) is rather common. In the era of highly active antiretroviral therapy (HAART), viral hepatitis could result in adverse outcomes in HIV+ patients. ...

Article

Epidemiology of aids defining conditions in Greece

Masgala, Aikaterini; Nikolopoulos, Georgios K.; Tsantes, Argirio E.; Paraskeva, D. (2004)

Objective: To examine the secular trends of all AIDS opportunistic infections to occur first (Ols) in Greece, by year, by gender and by mode of transmission. Methods: The study included all AIDS defining conditions reported ...

Article

HBV-DNA levels predict overall mortality in HIV/HBV coinfected individuals

Nikolopoulos, Georgios K.; Paraskeva, D.; Psichogiou, M.; Hatzakis, A. (2016)

The coinfection of Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) has been associated with increased death rates. However, the relevant research has mostly relied on serologic HBV testing [HBV surface antigen ...

Article

HIV epidemiology in Greece

Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzakis, A. (2008)

Greece has experienced early the effect of HIV/AIDS on morbidity and mortality. The era of highly active antiretroviral therapy has alleviated many of the consequences of the epidemic, however, HIV infection remains an ...

Article

HIV/AIDS: Recent advances in antiretroviral agents

Nikolopoulos, Georgios K.; Bonovas, Stefanos; Tsantes, Argirio E.; Sitaras, N. M. (2009)

Despite the considerable progress in antiretroviral therapy, the eradication of HIV-1 remains unfeasible. Therefore, novel agents are under investigation. The aim of this review is to summarize the conventional compounds, ...

Article

HIV/HBV co-infection and rate of antiretroviral treatment change after highly active antiretroviral treatment initiation in a cohort of HIV-infected patients in Greece

Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2010)

The current study investigated the impact of human immunodeficiency virus (HIV)/hepatitis B virus (HBV) co-infection on the rate of change of antiretroviral drugs after the initiation of highly active antiretroviral treatment ...

Article

Impact of hepatitis B virus infection on the progression of AIDS and mortality in HIV-infected individuals: A cohort study and meta-analysis

Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2009)

Background. The effect of hepatitis B virus (HBV) infection on the natural history of human immunodeficiency virus (HIV) disease remains uncertain. Therefore, a retrospective cohort study was conducted to examine the ...

Article

Is the mortality rate for septic shock really decreasing?

Christaki, Eirini; Opal, Steven M. (2008)

Survival rates for patients in septic shock have gradually improved in critical care units worldwide over the last 25 years. Further improvement will be predicated on the discovery of new therapies to disrupt the underlying ...

Article

Recent advances in the treatment of HIV/HBV and HIV/HCV co-infection

Masgala, Aikaterini; Bonovas, Stefanos; Nikolopoulos, Georgios K. (2012)

Concurrent infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in patients positive for human immunodeficiency virus (HIV) is relatively common. The treatment of co-infected individuals is rather complex ...