• Article  

      The application of HIV molecular epidemiology to public health 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Magiorkinis, Gkikas; Hodges-Mameletzis, I.; Hatzakis, A. (2016)
      HIV is responsible for one of the largest viral pandemics in human history. Despite a concerted global response for prevention and treatment, the virus persists. Thus, urgent public health action, utilizing novel interventions, ...
    • Article  

      Economic recession and emergence of an HIV-1 outbreak among drug injectors in Athens metropolitan area: A longitudinal study 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Fotiou, Anastasios; Tsiara, Chrissa G.; Paraskeva, D.; Sypsa, V.; Lazanas, Marios; Gargalianos, Panagiotis; Psichogiou, M.; Skoutelis, A.; Wiessing, L.; Friedman, Samuel R.; Jarlais, Don C. Des; Terzidou, M.; Kremastinou, Jenny; Malliori-Minerva, Melpomeni; Hatzakis, A. (2013)
      Background: During 2011, a dramatic increase (1600%) of reported HIV-1 infections among injecting drug users (IDUs) was noted in Athens, Greece. We herein assess the potential causal pathways associated with this outbreak. ...
    • Article  

      Enhanced HIV-1 surveillance using molecular epidemiology to study and monitor HIV-1 outbreaks among intravenous drug users (IDUs) in Athens and Bucharest 

      Paraskeva, D.; Paraschiv, S.; Sypsa, V.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Magiorkinis, Gkikas; Psichogiou, M.; Flampouris, Andreas; Mardarescu, Mariana; Niculescu, I.; Batan, Ionelia; Malliori-Minerva, Melpomeni; Otelea, D.; Hatzakis, A. (2015)
      Background: A significant increase in HIV-1 diagnoses was reported among Injecting Drug Users (IDUs) in the Athens (17-fold) and Bucharest (9-fold) metropolitan areas starting 2011. Methods: Molecular analyses were conducted ...
    • Article  

      The global spread of HIV-1 subtype B epidemic 

      Magiorkinis, Gkikas; Angelis, K.; Mamais, I.; Katzourakis, A.; Hatzakis, A.; Albert, J.; Lawyer, G.; Hamouda, O.; Struck, D.; Vercauteren, J.; Wensing, A.; Alexiev, I.; Åsjö, B.; Balotta, C.; Gomez, P.; Camacho, R. J.; Coughlan, S.; Griskevicius, A.; Grossman, Z.; Horban, A.; Kostrikis, L. G.; Lepej, S. J.; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paredes, R.; Pollack, S. M.; Puchhammer-Stöckl, E.; Schmit, J. C.; Sonnerborg, A.; Staneková, D.; Stanojevic, M.; Stylianou, D. C.; Boucher, C. A. B.; Nikolopoulos, Georgios K.; Vasylyeva, T. I.; Friedman, Samuel R.; Vijver, D. van de; Angarano, G.; Chaix, M. L.; Luca, A. de; Korn, K.; Loveday, C.; Soriano, V.; Yerly, S.; Zazzi, M.; Vandamme, A. M.; Paraskeva, D. (2016)
      Human immunodeficiency virus type 1 (HIV-1) was discovered in the early 1980s when the virus had already established a pandemic. For at least three decades the epidemic in the Western World has been dominated by subtype B ...
    • Article  

      HBV-DNA levels predict overall mortality in HIV/HBV coinfected individuals 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Psichogiou, M.; Hatzakis, A. (2016)
      The coinfection of Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) has been associated with increased death rates. However, the relevant research has mostly relied on serologic HBV testing [HBV surface antigen ...
    • Article  

      HIV epidemiology in Greece 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzakis, A. (2008)
      Greece has experienced early the effect of HIV/AIDS on morbidity and mortality. The era of highly active antiretroviral therapy has alleviated many of the consequences of the epidemic, however, HIV infection remains an ...
    • Article  

      HIV-1 outbreak among injecting drug users in Greece, 2011: A preliminary report 

      Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Paraskeva, D.; Antoniadou, Anastasia; Lazanas, Marios; Gargalianos, Panagiotis; Psychogiou, M.; Malliori-Minerva, Melpomeni; Kremastinou, Jenny; Hatzakis, A. (2011)
      A significant increase (more than 10-fold) in the number of newly diagnosed HIV-1 infections among injecting drug users (IDUs) was observed in Greece during the first seven months of 2011. Molecular epidemiology results ...
    • Article  

      HIV/AIDS: Recent advances in antiretroviral agents 

      Nikolopoulos, Georgios K.; Bonovas, Stefanos; Tsantes, Argirio E.; Sitaras, N. M. (2009)
      Despite the considerable progress in antiretroviral therapy, the eradication of HIV-1 remains unfeasible. Therefore, novel agents are under investigation. The aim of this review is to summarize the conventional compounds, ...
    • Article  

      Impact of HIV type 1 DNA levels on spontaneous disease progression: A meta-analysis 

      Tsiara, Chrissa G.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Goujard, Cecile; Katzenstein, Terese L.; Minga, Albert K.; Rouzioux, C.; Hatzakis, A. (2012)
      Several studies have reported the prognostic strength of HIV-1 DNA with variable results however. The aims of the current study were to estimate more accurately the ability of HIV-1 DNA to predict progression of HIV-1 ...
    • Article  

      Increasing prevalence of HIV-1 subtype a in Greece: Estimating epidemic history and origin 

      Paraskeva, D.; Magiorkinis, Emmanouil; Magiorkinis, Gkikas; Sypsa, V.; Paparizos, V.; Lazanas, Marios; Gargalianos, Panagiotis; Antoniadou, Anastasia; Panos, G.; Chrysos, Georgios; Sambatakou, H.; Karafoulidou, Anastasia; Skoutelis, A.; Kordossis, Theodoros; Koratzanis, Georgios; Theodoridou, M.; Daikos, Georgios L.; Nikolopoulos, Georgios K.; Pybus, O. G.; Hatzakis, A. (2007)
      Background. In North America and Europe, human immunodeficiency virus (HIV)-1 infection has typically been dominated by subtype B transmission. More recently, however, non-B subtypes have been increasingly reported in ...
    • Article  

      Prevalence of drug resistance among HIV-1 treatment-naive patients in Greece during 2003–2015: Transmitted drug resistance is due to onward transmissions 

      Paraskeva, D.; Kostaki, Evangelia-Georgia; Magiorkinis, Gkikas; Gargalianos, Panagiotis; Xylomenos, G.; Magiorkinis, Emmanouil; Lazanas, Marios; Chini, M.; Nikolopoulos, Georgios K.; Skoutelis, A.; Papastamopoulos, V.; Antoniadou, Anastasia; Papadopoulos, A.; Psichogiou, M.; Daikos, Georgios L.; Oikonomopoulou, M.; Zavitsanou, A.; Chrysos, Georgios; Paparizos, V.; Kourkounti, S.; Sambatakou, H.; Sipsas, N. V.; Lada, M.; Panagopoulos, P.; Maltezos, E.; Drimis, S.; Hatzakis, A. (2017)
      Background The prevalence of HIV-1 drug resistance among treatment-naïve patients ranges between 8.3% and 15% in Europe and North America. Previous studies showed that subtypes A and B were the most prevalent in the Greek ...
    • Article  

      Recent advances in the treatment of HIV/HBV and HIV/HCV co-infection 

      Masgala, Aikaterini; Bonovas, Stefanos; Nikolopoulos, Georgios K. (2012)
      Concurrent infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in patients positive for human immunodeficiency virus (HIV) is relatively common. The treatment of co-infected individuals is rather complex ...