• Article  

      Avascular necrosis in five patients with human immunodeficiency virus (HIV) infection 

      Clark, B. M.; Zenios, Michalis; Wilkins, E. G. L.; Sochart, D. H. (2003)
      Avascular necrosis (AVN) of bone occurring in patients infected with Human Immunodeficiency Virus (HIV) has been well documented in recent literature. Contributing factors may include drug treatment (steroids and protease ...
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      A chemokine receptor CCR2 allele delays HIV-1 disease progression and is associated with a CCR5 promoter mutation 

      Deutsch, L.; Kostrikis, Leontios G.; Huang, Y.; Moore, J. P.; Wolinsky, S. M.; Zhang, L.; Guo, Y.; Phair, J.; Neumann, A. U.; Ho, David D. (1998)
      Viral and host factors influence the rate of HIV-1 disease progression. For HIV-1 to fuse, a CD4+ cell must express a co-receptor that the virus can use. The chemokine receptors CCR5 and CXCR4 are used by R5 and X4 viruses, ...
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      CXCR4 mediates entry and productive infection of syncytia-inducing (x4) hiv-1 strains in primary macrophages 

      Valentin, A.; Trivedi, H.; Lu, W.; Kostrikis, Leontios G.; Pavlakis, G. N. (2000)
      CCR5 and CXCR4 are the main coreceptors for non-syncytia-inducing (NSI) and syncytia-inducing (SI) HIV-1 strains, respectively. NSI HIV-1 isolates do not infect either human lymphoid or monocytoid cell lines, and this ...
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      Estimating HIV incidence and number of undiagnosed individuals living with HIV in the European union/ European economic area, 2015 

      Pharris, Anastasia; Quinten, C.; Noori, T.; Amato-Gauci, A. J.; Sighem, A. van; Schmid, D.; Rueckerl, I.; Zangerle, R.; Sasse, A.; Beckhoven, D. van; Denauw, F.; Varleva, T.; Georgieva, V.; Blazic, T. N.; Pavlic, J.; Begovac, J.; Koliou, M.; Hadjihannas, L.; Demetriou, A.; Maly, M.; Šikolová, V.; Cowan, Susan; Fouchard, J.; Rüütel, K.; Pääsukene, A. L.; Liitsola, K.; Salminen, M.; Brummer-Korvenkontio, H.; Cazein, F.; Pillonel, J.; Lot, F.; Comboroure, J.-C.; Gunsenheimer-Bartmeyer, Barbara; Heiden, M. A. Der; Kupfer, G.; Marcus, U.; Nikolopoulos, Georgios K.; Paraskeva, D.; Konte, Vasileia; Dudas, M.; Szalay, K.; Briem, H.; Sigmundsdottir, G.; Igoe, D.; O’Donnell, K.; Hurley, C.; Lyons, F.; Suligoi, B.; Caraglia, A.; Konova, S.; Erne, S.; Caplinskiene, I.; Fischer, A.; Hoffmann, P.; Melillo, J. M.; Melillo, T.; Coul, Eline Op de; David, S.; Blystad, H.; Myrberg, A. J.; Rosinska, M.; Wawer, I.; Mansinho, K.; Martins, H. C.; Melillo, T.; Mardarescu, Mariana; Truska, P.; Mikas, J.; Klavs, I.; Diaz, Alejandro; Nuñez, O.; Castillo, O.; Avdicova, Maria; Sonnerborg, A.; Kirwan, P.; Chau, C.; Okala, S.; Brown, A.; Delpech, Valerie (2016)
      Since 2011, human immunodeficiency virus (HIV) incidence appears unchanged in the European Union/ European Economic Area with between 29,000 and 33,000 new cases reported annually up to 2015. Despite evidence that HIV ...
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      High-burden epidemics in Greece in the era of economic crisis. Early signs of a public health tragedy 

      Bonovas, Stefanos; Nikolopoulos, Georgios K. (2012)
      Background. Economic hardships have unleashed epidemics of infectious diseases in many countries in the past. In the era of the current financial crisis in Greece, it is interesting to assess the preliminary evidence ...
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      Human immunodeficiency virus in injecting drug users in Europe following a reported increase of cases in Greece and Romania, 2011 

      Pharris, Anastasia; Wiessing, L.; Sfetcu, O.; Hedrich, D.; Botescu, A.; Fotiou, Anastasios; Nikolopoulos, Georgios K.; Malliori-Minerva, Melpomeni; Salminen, M.; Suk, J. E.; Griffiths, P.; Laar, M. J. van de (2011)
      Greece and Romania reported an increased number of HIV cases among injecting drug users (IDUs) during 2011. Most European countries reported no changes in the rate of newly diagnosed cases of HIV or HIV prevalence in IDUs; ...
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      Increasing prevalence of HIV-1 subtype a in Greece: Estimating epidemic history and origin 

      Paraskeva, D.; Magiorkinis, Emmanouil; Magiorkinis, Gkikas; Sypsa, V.; Paparizos, V.; Lazanas, Marios; Gargalianos, Panagiotis; Antoniadou, Anastasia; Panos, G.; Chrysos, Georgios; Sambatakou, H.; Karafoulidou, Anastasia; Skoutelis, A.; Kordossis, Theodoros; Koratzanis, Georgios; Theodoridou, M.; Daikos, Georgios L.; Nikolopoulos, Georgios K.; Pybus, O. G.; Hatzakis, A. (2007)
      Background. In North America and Europe, human immunodeficiency virus (HIV)-1 infection has typically been dominated by subtype B transmission. More recently, however, non-B subtypes have been increasingly reported in ...
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      A novel simple QSAR model for the prediction of anti-HIV activity using multiple linear regression analysis 

      Afantitis, Antreas; Melagraki, G.; Sarimveis, H.; Koutentis, Panayiotis Andreas; Markopoulos, J.; Igglessi-Markopoulou, O. (2006)
      A quantitative-structure activity relationship was obtained by applying Multiple Linear Regression Analysis to a series of 80 1-[2-hydroxyethoxy-methyl] -6-(phenylthio) thymine (HEPT) derivatives with significant anti-HIV ...
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      Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy 

      Sharkey, M. E.; Teo, I.; Greenough, T.; Sharova, N.; Luzuriaga, K.; Sullivan, J. L.; Bucy, R. P.; Kostrikis, Leontios G.; Haase, A.; Veryard, C.; Davaro, R. E.; Cheeseman, S. H.; Daly, J. S.; Bova, C.; Ellison III, R. T.; Mady, B.; Lai, K. K.; Moyle, G.; Nelson, M.; Gazzard, B.; Shaunak, S.; Stevenson, M. (2000)
      Treatment of HIV-1-infected individuals with a combination of anti- retroviral agents results in sustained suppression of HIV-1 replication, as evidenced by a reduction in plasma viral RNA to levels below the limit of ...
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      Persistent HIV-1 infection of natural killer cells in patients receiving highly active antiretroviral therapy 

      Valentin, A.; Rosati, M.; Patenaude, D. J.; Hatzakis, Angelos E.; Kostrikis, Leontios G.; Lazanas, Marios C.; Wyvill, K. M.; Yarchoan, R.; Pavlakis, G. N. (2002)
      We have identified a subset of CD56+CD3- human natural killer (NK) cells that express CD4 and the HIV coreceptors CCR5 and CXCR4. These cells can be productively infected in vitro by both CCR5- and CXCR4-using molecular ...
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      Re-analysis of human immunodeficiency virus type 1 isolates from Cyprus and Greece, initially designated 'subtype I', reveals a unique complex A/G/H/K/? mosaic pattern 

      Paraskevis, Dimitrios N.; Magiorkinis, M.; Vandamme, A. M.; Kostrikis, Leontios G.; Hatzakis, Angelos E. (2001)
      Human immunodeficiency virus type 1 (HIV-1) has been classified into three main groups and 11 distinct subtypes. Moreover, several circulating recombinant forms (CRFs) of HIV-1 have been recently documented to have spread ...
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      Spectral genotyping of human alleles 

      Kostrikis, Leontios G.; Tyagi, S.; Mhlanga, M. M.; Ho, David D.; Kramer, F. R. (1998)
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      Trends in HIV surveillance data in the EU/EEA, 2005 to 2014: New HIV diagnoses still increasing in men who have sex with men 

      Pharris, Anastasia; Quinten, C.; Tavoschi, L.; Spiteri, G.; Amato-Gauci, A. J.; Schmid, D.; Sasse, A.; Beckhoven, D. Van; Varleva, T.; Blazic, Tatjana Nemeth; Koliou, M.; Hadjihannas, L.; Maly, M.; Cowan, Susan; Rüütel, K.; Liitsola, K.; Salminen, M.; Cazein, F.; Pillonel, J.; Lot, F.; Gunsenheimer-Bartmeyer, Barbara; Nikolopoulos, Georgios K.; Paraskeva, D.; Dudas, M.; Briem, H.; Sigmundsdottir, G.; Igoe, D.; O’Donnell, K.; O’Flanagan, D.; Suligoi, B.; Konova, S.; Erne, S.; Caplinskiene, I.; Jean-Schmit, C.; Melillo, J. M.; Melillo, T.; Coul, E. Op De; Blystad, H.; Rosinska, M.; Diniz, A.; Mardarescu, Mariana; Truska, P.; Klavs, I.; Diez, M.; Avdicova, Maria; Delpech, Valerie (2015)
      Human immunodeficiency virus (HIV) transmission remains significant in Europe. Rates of acquired immunodeficiency syndrome (AIDS) have declined, but not in all countries. New HIV diagnoses have increased among native and ...