• Conference Object  

      Acceleration-dependent sampling for ingestible endoscopic imaging capsule 

      Demosthenous, P.; Georgiou, J. (IEEE, 2012)
      A methodology is proposed for regulating the image-acquisition sampling rate of endoscopic capsules. The proposed method utilizes acceleration information to increase the sampling rate during rapid movement. In order to ...
    • Article  

      Accurate measurement of microbubble response to ultrasound with a diagnostic ultrasound scanner 

      Keravnou, Christina; Mannaris, Christophoros; AVERKIOU, MICHALAKIS A. (2015)
      Ultrasound and microbubbles are often used to enhance drug delivery and the suggested mechanisms are extravasation and sonoporation. Drug delivery schemes with ultrasound and microbubbles at both low and high acoustic ...
    • Article  

      Atomic Force Microscopy Probing of Cancer Cells and Tumor Microenvironment Components 

      Stylianou, A.; Stylianopoulos, T. (2016)
      Cancer cells have different characteristics from normal cells in terms of morphology, cell–cell interactions, cytoskeleton organization, cell growth rates, and cell-extracellular matrix interactions. Although the clarification ...
    • Article  

      Automatic respiratory gating for perfusion quantification of DCEUS 

      Christofides, Damianos; AVERKIOU, MICHALAKIS A.; Leen, Edward (2013)
      A novel automatic respiratory gating (ARG) algorithm for ultrasound is presented. The ARG algorithm was applied on dual contrast imaging (contrast/tissue) loops in order to remove respiratory motion artifacts from dynamic ...
    • Article  

      Cancer of unknown primary origin 

      Briassoulis, E. Ch; Pavlidis, Nicholas (1997)
      About 3 % of all cancer patients suffer from cancer of unknown primary origin. These patients present with metastatic disease for which a primary site cannot be detected at the time of diagnosis. Sophisticated diagnostic ...
    • Article  

      Doxorubicin liposome-loaded microbubbles for contrast imaging and ultrasound-triggered drug delivery 

      Escoffre, Jean-Michel; Mannaris, Christophoros; Geers, Bart; Novell, Anthony; Lentacker, Ine; Averkiou, Michalakis A.; Bouakaz, Ayache (2013)
      Targeted drug delivery under image guidance is gaining more interest in the drug-delivery field. The use of microbubbles as contrast agents in diagnostic ultrasound provides new opportunities in noninvasive image-guided ...
    • Article  

      Evaluation of the Accuracy of Liver Lesion DCEUS Quantification With Respiratory Gating 

      Christofides, Damianos; Leen, Edward; AVERKIOU, MICHALAKIS A. (2016)
      Confidence in the accuracy of dynamic contrast enhanced ultrasound (DCEUS) quantification parameters is imperative for the correct diagnosis of liver lesion perfusion characteristics. An important source of uncertainty in ...
    • Article  

      Harmonic generation with a dual frequency pulse 

      Keravnou, Christina P.; AVERKIOU, MICHALAKIS A. (2013)
      Nonlinear imaging was utilized in commercial ultrasound systems over the last 15 years offering major advantages in many clinical applications. In this work, pulsing schemes (pulse inversion, power modulated pulse inversion ...
    • Article  

      Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging 

      Vakoc, B. J.; Lanning, R. M.; Tyrrell, J. A.; Padera, T. P.; Bartlett, L. A.; Stylianopoulos, T.; Munn, L. L.; Tearney, G. J.; Fukumura, D.; Jain, R. K.; Bouma, Brett E. (2009)
      Intravital multiphoton microscopy has provided powerful mechanistic insights into health and disease and has become a common instrument in the modern biological laboratory. The requisite high numerical aperture and exogenous ...
    • Article  

      Vascular flow and perfusion imaging with ultrasound contrast agents 

      Bruce, M.; Averkiou, Michalakis A.; Tiemann, Klaus; Lohmaier, S. FAU; Powers, J. E.; Beach, K. (2004)
      Current techniques for imaging ultrasound (US) contrast agents (UCA) make no distinction between low-velocity microbubbles in the microcirculation and higher-velocity microbubbles in the larger vasculature. A combination ...