Browsing by Subject "Inheritance"
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The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: A mendelian randomization meta-analysis (2014)Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased in individuals carrying the 4G allele at position -675 of the PAI-1 gene. In turn, overexpression of PAI-1 has been found ...
(2007)We propose here a simple and robust approach for meta-analysis of molecular association studies. Making use of the binary structure of the data, and by treating the genotypes as independent variables in a logistic regression, ...