Browsing by Subject "Inhibition"
Now showing items 1-9 of 9
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Article
Crystallographic and computational studies on 4-phenyl-N-(β-D- glucopyranosyl)-1H-1,2, 3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: Comparison with α-D-glucose, N-acetyl-β-D- glucopyranosylamine and N-benzoyl-N′-β-D-glucopyranosyl urea binding
(2008)4-Phenyl-N-(β-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide (glucosyltriazolylacetamide) has been studied in kinetic and crystallographic experiments with glycogen phosphorylase b (GPb), in an effort to utilize its ...
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Article
Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase
(2005)Glycogen phosphorylase (GP) is currently exploited as a target for inhibition of hepatic glycogenolysis under high glucose conditions. Spirohydantoin of glucopyranose and N-acetyl-β-D-glucopyranosylamine have been identified ...
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Article
Near Poisson-type firing produced by concurrent excitation and inhibition
(2000)The effect of inhibition on the firing variability is examined in this paper using the biologically-inspired temporal noisy-leaky integrator (TNLI) neuron model. The TNLI incorporates hyperpolarising inhibition with negative ...
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Article
On the firing variability of the integrate-and-fire neurons with partial reset in the presence of inhibition
(2002)It has been reported (Phys. Rev. Lett. 82 (1999) 4731) that the firing variability of integrate-and-fire (I&F) neurons is strongly dependent on the level of inhibitory input unlike the Hodgkin-Huxley and FitzHugh-Nagumo ...
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Article
On the structure and development of executive functions in middle and late childhood: Remodeling and Commentary on Brydges, Fox, Reid, and Anderson
(2015)This is a commentary on the study presented by Brydges, Fox, Reid, and Anderson (2014) on the structure and development of executive functions in middle and late childhood. We argue that the modeling approach adopted by ...
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Article
Risky and aggressive driving in young adults: Personality matters
(2011)Young, novice drivers constitute a disproportionate percentage of fatalities and injuries in road traffic accidents around the world. This study, attempts to identify motivational factors behind risky driving behavior, and ...
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Article
A spiking neuron model: Applications and learning
(2002)This paper presents a biologically inspired, hardware-realisable spiking neuron model, which we call the Temporal Noisy-Leaky Integrator (TNLI). The dynamic applications of the model as well as its applications in Computational ...
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Article
Synchrony measure for a neuron driven by excitatory and inhibitory inputs and its adaptation to experimentally-recorded data
(2017)The aim of the current work is twofold: firstly to adapt an existing method measuring the input synchrony of a neuron driven only by excitatory inputs in such a way so as to account for inhibitory inputs as well and secondly ...
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Doctoral Thesis Open Access
Γνωστικό μοντέλο εντοπισμού και αντιμετώπισης της διαταραχής ελλειμματικής προσοχής - υπερκινητικότητας (ΔΕΠ-Υ) (μέσω ηλεκτρονικού υπολογιστή) σε μαθητές πρώτης σχολικής ηλικίας
(Πανεπιστήμιο Κύπρου, Σχολή Κοινωνικών Επιστημών και Επιστημών Αγωγής / University of Cyprus, Faculty of Social Sciences and Education, 2009-05)Αναπτύχθηκε και εφαρμόστηκε ένα ηλεκτρονικό Γνωστικό Θεραπευτικό Πρόγραμμα (ΓΘΠ) για την αντιμετώπιση της ΔΕΠ-Υ. Η ανάπτυξη του ΓΘΠ στηρίχθηκε στις τέσσερις εκτελεστικές λειτουργίες (αναστολή, προσοχή, εργαζόμενη μνήμη και ...