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Browsing by Subject "Innate immunity"

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    • Article  

      The complex pathogenesis of bacteremia: From antimicrobial clearance mechanisms to the genetic background of the host 

      Christaki, Eirini; Giamarellos-Bourboulis, Evangelos J. (2014)
      Bacteremia develops when bacteria manage to escape the host immune mechanisms or when the otherwise well-orchestrated immune response fails to control bacterial spread due to inherent or acquired immune defects that are ...

    • Article  

      Host immune response in sepsis due to ventilator-associated pneumonia: How is it different? 

      Christaki, Eirini (2009)
      Current evidence regarding potentially different host response mechanisms in sepsis according to the type of initiating infection is sporadic. It is possible that alterations in cell populations, variations in effector ...

    • Article  

      Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimocrobial peptide gene expression 

      Apidianakis, Yiorgos; Mindrinos, M. N.; Xiao, W.; Lau, G. W.; Baldini, R. L.; Davis, R. W.; Rahme, L. G. (2005)
      Insights into the host factors and mechanisms mediating the primary host responses after pathogen presentation remain limited, due in part to the complexity and genetic intractability of host systems. Here, we employ the ...

    • Article  

      Serotonin reuptake inhibitor antidepressants (SSRIs) against atherosclerosis 

      Wozniak, Greta; Toska, Aikaterini; Saridi, Maria; Mouzas, Odysseas (2011)
      Selective serotonin reuptake inhibitors (SSRIs) are a class of drug widely used for treatment of mood disorders, including depression and cardiovascular disease. A search for related articles in the PubMed database was ...

    • Article  

      Targeting pattern recognition receptors (PRR) for vaccine adjuvantation: From synthetic PRR agonists to the potential of defective interfering particles of viruses 

      Vasou, A.; Sultanoglu, N.; Goodbourn, S.; Randall, R. E.; Kostrikis, Leontios G. (2017)
      Modern vaccinology has increasingly focused on non-living vaccines, which are more stable than live-attenuated vaccines but often show limited immunogenicity. Immunostimulatory substances, known as adjuvants, are traditionally ...

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