Browsing by Subject "Kit"

Now showing items 1-2 of 2

    • Article  

      Molecular subtypes of gastrointestinal stromal tumors and their prognostic and therapeutic implications 

      Szucs, Z.; Thway, K.; Fisher, Cyril; Bulusu, Ramesh; Constantinidou, Anastasia; Benson, Charlotte; Graaf, W. T. A. van der; Jones, Robin Lewis (2017)
      Gastrointestinal stromal tumors (GISTs) are composed of various molecular subtypes, with differing prognostic and predictive relevance. Previously, tumors lacking mutations in the KIT and PDGFRA genes have been designated ...
    • Article  

      Promising novel therapeutic approaches in the management of gastrointestinal stromal tumors 

      Szucs, Z.; Thway, K.; Fisher, Cyril; Bulusu, Ramesh; Constantinidou, Anastasia; Benson, Charlotte; Graaf, W. T. A. van der; Jones, Robin Lewis (2017)
      Primary and secondary resistance to currently available licensed tyrosine kinase inhibitors poses a real clinical challenge in the management of advanced gastrointestinal stromal tumors. Within the frame of early phase ...