Browsing by Subject "Linear Models"

Article

A novel QSPR model for predicting θ (lower critical solution temperature) in polymer solutions using molecular descriptors

Melagraki, G.; Afantitis, Antreas; Sarimveis, H.; Koutentis, Panayiotis Andreas; Markopoulos, J.; Igglessi-Markopoulou, O. (2007)

In this study, we present a new model that has been developed for the prediction of θ, (lower critical solution temperature) using a database of 169 data points that include 12 polymers and 67 solvents. For the characterization ...

Article

Analysis of polyphenols using capillary zone electrophoresis - Determination of the most effective wine sample pre-treatment method

Nicolaou, I. N.; Kapnissi‐Christodoulou, Constantina P. (2010)

A simple CZE method has been developed for the simultaneous determination of eight polyphenolic compounds. The influence of several experimental conditions such as buffer (concentration and pH) and temperature were studied. ...

Article

A combined LS-SVM & MLR QSAR workflow for predicting the inhibition of CXCR3 receptor by quinazolinone analogs

Afantitis, Antreas; Melagraki, G.; Sarimveis, H.; Koutentis, Panayiotis Andreas; Igglessi-Markopoulou, O.; Kollias, G. (2010)

AnovelQSARworkflowis constructed that combines MLR with LS-SVM classification techniques for the identification of quinazolinone analogs as "active" or "nonactive" CXCR3 antagonists. The accuracy of the LS-SVM classification ...

Article

Identification of a series of novel derivatives as potent HCV inhibitors by a ligand-based virtual screening optimized procedure

Melagraki, G.; Afantitis, Antreas; Sarimveis, H.; Koutentis, Panayiotis Andreas; Markopoulos, J.; Igglessi-Markopoulou, O. (2007)

This paper presents the results of a ligand-based virtual screening optimized procedure on 98 compounds which have been recently evaluated as inhibitors of genotype 1 HCV polymerase. First, quantitative structure-activity ...

Article

Investigation of substituent effect of 1-(3,3-diphenylpropyl)-piperidinyl phenylacetamides on CCR5 binding affinity using QSAR and virtual screening techniques

Afantitis, Antreas; Melagraki, G.; Sarimveis, H.; Koutentis, Panayiotis Andreas; Markopoulos, J.; Igglessi-Markopoulou, O. (2006)

A linear quantitative-structure activity relationship model is developed in this work using Multiple Linear Regression Analysis as applied to a series of 51 1-(3,3-diphenylpropyl)-piperidinyl phenylacetamides derivatives ...

Article

Island species richness increases with habitat diversity

Hortal, J.; Triantis, Kostas A.; Meiri, S.; Thébault, E.; Sfenthourakis, Spyros (2009)

Species richness is commonly thought to increase with habitat diversity. However, a recent theoretical model aiming to unify niche and island biogeography theories predicted a hump-shaped relationship between richness and ...

Article

Novel approach to fast determination of cholesterol oxidation products in Cypriot foodstuffs using ultra-performance liquid chromatography-tandem mass spectrometry

Georgiou, Christiana A.; Constantinou, Michalis S.; Andreou, Rafaella; Hapeshi, Evroula; Fatta‐Kassinos, Despo; Kapnissi‐Christodoulou, Constantina P. (2016)

This paper reports the development and validation of a new method based on ultra-performance LC coupled to MS/MS for the simultaneous determination of four cholesterol oxidation products (COPs) in foodstuffs in only 4.1 ...

Article

Novel approach to fast determination of cholesterol oxidation products in Cypriot foodstuffs using ultra-performance liquid chromatography-tandem mass spectrometry

Georgiou, Christiana A.; Constantinou, Michalis S.; Andreou, Rafaella; Hapeshi, E.; Fatta-Kassinos, Despo; Kapnissi-Christodoulou, Constantina (2016)

This paper reports the development and validation of a new method based on ultra-performance LC coupled to MS/MS for the simultaneous determination of four cholesterol oxidation products (COPs) in foodstuffs in only 4.1 ...

Article

A novel simple QSAR model for the prediction of anti-HIV activity using multiple linear regression analysis

Afantitis, Antreas; Melagraki, G.; Sarimveis, H.; Koutentis, Panayiotis Andreas; Markopoulos, J.; Igglessi-Markopoulou, O. (2006)

A quantitative-structure activity relationship was obtained by applying Multiple Linear Regression Analysis to a series of 80 1-[2-hydroxyethoxy-methyl] -6-(phenylthio) thymine (HEPT) derivatives with significant anti-HIV ...

Article

Qualitative and quantitative determination of COPs in cypriot meat samples using HPLC determination of the most effective sample preparation procedure

Georgiou, Christiana A.; Kapnissi‐Christodoulou, Constantina P. (2013)

This research work describes the development of a fast high-performance liquid chromatography method for the simultaneous determination of five important cholesterol oxidation products (COPs). The influence of various ...

Article

Testing alternative hypotheses for evolutionary diversification in an african songbird: Rainforest refugia versus ecological gradients

Kirschel, A. N. G.; Slabbekoorn, H.; Blumstein, Daniel T.; Cohen, R. E.; de Kort, S. R.; Buermann, W.; Smith, T. B. (2011)

Geographic isolation in rainforest refugia and local adaptation to ecological gradients may both be important drivers of evolutionary diversification. However, their relative importance and the underlying mechanisms of ...