Browsing by Subject "Macaque"

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    • Article  

      Dramatic rise in plasma viremia after CD8+ T cell depletion in simian immunodeficiency virus-infected macaques 

      Jin, X.; Bauer, D. E.; Tuttleton, S. E.; Lewin, S.; Gettie, A.; Blanchard, J.; Irwin, C. E.; Safrit, J. T.; Mittler, J.; Weinberger, L.; Kostrikis, Leontios G.; Zhang, L.; Perelson, A. S.; Ho, David D. (1999)
      To determine the role of CD8+ T cells in controlling simian immunodeficiency virus (SIV) replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 monoclonal antibody, OKT8F. There was ...