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Browsing by Subject "Models"

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    • Article  

      Aerial Oxidation of a VIV-Iminopyridine Hydroquinonate Complex: A Trap for the VIV-Semiquinonate Radical Intermediate 

      Stylianou, M.; Drouza, C.; Giapintzakis, John; Athanasopoulos, G. I.; Keramidas, A. D. (2015)
      The reaction of 2,5-bis[N,N′-bis(2-pyridyl-aminomethyl)aminomethyl]-p-hydroquinone (H2bpymah) with VO2+ salts in acetonitrile or water at a low pH (2.2-3.5) results in the isolation of [VIV(O)(Cl)2(μ-bpymah)], the ...

    • Conference Object  

      An analytical model for the calculation of the Expected Miss Ratio in faulty caches 

      Sánchez, D.; Sazeides, Yiannakis; Aragón, J. L.; García, J. M. (2011)
      Technology scaling improvement is affecting the reliability of ICs due to increases in static and dynamic variations as well as wear-out failures. This is particularly true for caches that dominate the area of modern ...

    • Article  

      Antirestenotic effects of a novel polymer-coated d-24851 eluting stent. Experimental data in a rabbit iliac artery model 

      Lysitsas, Dimitrios N.; Katsouras, Christos S.; Papakostas, John C.; Toumpoulis, Ioannis K.; Angelidis, Charalampos; Bozidis, Petros; Thomas, Christopher G.; Seferiadis, C.; Psychoyios, Nikolaos; Frillingos, Stathis; Pavlidis, Nicholas; Marinos, Euaggelos; Khaldi, Lubna; Sideris, Dimitris A.; Michalis, Lampros K. (2007)
      Experimental and clinical data suggest that stents eluting antiproliferative agents can be used for the prevention of in-stent restenosis. Here we investigate in vitro the antiproliferative and apoptotic effect of D-24851 ...

    • Article  

      Big events in Greece and HIV infection among people who inject drugs 

      Nikolopoulos, Georgios K.; Sypsa, V.; Bonovas, Stefanos; Paraskeva, D.; Malliori-Minerva, Melpomeni; Hatzakis, A.; Friedman, Samuel R. (2015)
      Big Events are processes like macroeconomic transitions that have lowered social well-being in various settings in the past. Greece has been hit by the global crisis and experienced an HIV outbreak among people who inject ...

    • Article  

      Biphasic modeling of brain tumor biomechanics and response to radiation treatment 

      Angeli, S.; Stylianopoulos, T. (2016)
      Biomechanical forces are central in tumor progression and response to treatment. This becomes more important in brain cancers where tumors are surrounded by tissues with different mechanical properties. Existing mathematical ...

    • Article  

      Brownian-like kinematics of ball milling for particulate structural modeling 

      Doumanidis, C. C.; Kaabi, H. A. Al; Alzaabi, A. S. M.; Gunduz, I. E.; Rebholz, Claus; Doumanidis, C. C. (2016)
      Ball milling motion has been previously studied through computationally expensive, off-line experimental video processing and numerical simulations by the discrete element method. This research establishes a more efficient ...

    • Article  

      Cationic nanoparticles have superior transvascular flux into solid tumors: Insights from a mathematical model 

      Stylianopoulos, T.; Soteriou, K.; Fukumura, D.; Jain, R. K. (2013)
      Despite their great promise, only a few nanoparticle formulations have been approved for clinical use in oncology. The failure of nano-scale drugs to enhance cancer therapy is in large part due to inefficient delivery. To ...

    • Article  

      Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors 

      Stylianopoulos, T.; Martin, J. D.; Chauhan, V. P.; Jain, S. R.; Diop-Frimpong, B.; Bardeesy, N.; Smith, B. L.; Ferrone, C. R.; Hornicek, F. J.; Boucher, Y.; Munn, L. L.; Jain, R. K. (2012)
      The presence of growth-induced solid stresses in tumors has been suspected for some time, but these stresses were largely estimated using mathematical models. Solid stresses can deform the surrounding tissues and compress ...

    • Article  

      Cell-nuclear data reduction and prognostic model selection in bladder tumor recurrence 

      Tasoulis, Dimitris K.; Spyridonos, Panagiota; Plagianakos, Vassilis P.; Ravazoula, Panagiota; Nikiforidis, Georgios; Vrahatis, Michael N. (2006)
      OBJECTIVE: The paper aims at improving the prediction of superficial bladder recurrence. To this end, feedforward neural networks (FNNs) and a feature selection method based on unsupervised clustering, were employed. ...

    • Article  

      Coevolution of solid stress and interstitial fluid pressure in tumors during progression: Implications for vascular collapse 

      Stylianopoulos, T.; Martin, J. D.; Snuderl, M.; Mpekris, F.; Jain, S. R.; Jain, R. K. (2013)
      The stress harbored by the solid phase of tumors is known as solid stress. Solid stress can be either applied externally by the surrounding normal tissue or induced by the tumor itself due to its growth. Fluid pressure is ...

    • Article  

      Combining two strategies to improve perfusion and drug delivery in solid tumors 

      Stylianopoulos, T.; Jain, R. K. (2013)
      Blood perfusion in tumors can be significantly lower than that in the surrounding normal tissue owing to the leakiness and/or compression of tumor blood vessels. Impaired perfusion reduces oxygen supply and results in a ...

    • Conference Object  

      Computational modeling of visual selective attention 

      Neokleous,Kleanthis C.; Schizas, Christos N. (2011)
      An overview of a nerocomputational model of visual selective attention that has been properly implemented is presented in this abstract. Visual selective attention is a fundamental function of human cognition and a highly ...

    • Article  

      Computational predictions of the tensile properties of electrospun fibre meshes: Effect of fibre diameter and fibre orientation 

      Barocas, V. Η; Stylianopoulos, T.; Bashur, C. A.; Goldstein, A. S.; Guelcher, S. A. (2008)
      The mechanical properties of biomaterial scaffolds are crucial for their efficacy in tissue engineering and regenerative medicine. At the microscopic scale, the scaffold must be sufficiently rigid to support cell adhesion, ...

    • Conference Object  

      Design and development of a haptic peg-board exercise for the rehabilitation of people with multiple sclerosis 

      Xydas, E. G.; Louca, Loucas S. (Affiliation: Mechanical and Manufacturing Engineering Department, University of Cyprus, P.O. Box: 20537, Nicosia, CyprusAffiliation: Mechanical and Manufacturing Engineering Department, University of CyprusCorrespondence Address: Xydas, E. G.Mechanical and Manufacturing Engineering Department, University of Cyprus, P.O. Box: 20537, Nicosia, Cyprusemail: mep4ex01@ucy.ac.cy, 2007)
      Peg-in-Hole methods, like the Nine Hole Peg-Board Test (NHPT) and the Perdue board are widely employed for the functional assessment and therapy of the upper limbs of people with Multiple Sclerosis (MS). Such passive devices ...

    • Book Chapter  

      Development and test of an instrument that investigates teachers' beliefs, attitudes and intentions concerning the educational use of simulations 

      Zacharia, Zacharias C.; Rotsaka, Ioanna; Hovardas, Tasos (IAP Information Age Publishing, 2011)
      The purpose of this research was to develop an instrument, namely, a questionnaire that investigates teachers' beliefs, attitudes, and intentions concerning the use of simulations for educational purposes, including for ...

    • Report  

      The Effects of Background Variables on the Participation of Students in Social Actions 

      Papanastasiou, Constantinos; Koutselini, Mary (2002)
      This paper examines the extent to which home background and school climate affects ninth grade students' social and political understanding and participation. Using the data from the student questionnaires (n=3106) of the ...

    • Article  

      Evolution of osmotic pressure in solid tumors 

      Voutouri, C.; Stylianopoulos, T. (2014)
      The mechanical microenvironment of solid tumors includes both fluid and solid stresses. These stresses play a crucial role in cancer progression and treatment and have been analyzed rigorously both mathematically and ...

    • Article  

      Explaining Differences in Subjective Well-Being Across 33 Nations Using Multilevel Models: Universal Personality, Cultural Relativity, and National Income 

      Cheng, Cecilia; Cheung, Mike W.-L.; Montasem, Alex; Panayiotou, Alexia (2016)
      This multinational study simultaneously tested three prominent hypotheses–universal disposition, cultural relativity, and livability–that explained differences in subjective well-being across nations. We performed multilevel ...

    • Article  

      Fcγ receptor polymorphisms and their association with periodontal disease: A meta-analysis 

      Dimou, Niki L.; Nikolopoulos, Georgios K.; Hamodrakas, Stavros J.; Bagos, Pantelis G. (2010)
      Aim: A systematic review and a meta-analysis were conducted in order to investigate the potential association of Fcγ receptor (FcγR) polymorphisms with susceptibility to aggressive and chronic periodontal disease. Materials ...

    • Article  

      Generalized least squares for assessing trends in cumulative meta-analysis with applications in genetic epidemiology 

      Bagos, Pantelis G.; Nikolopoulos, Georgios K. (2009)
      Objective: Cumulative meta-analysis allows the evaluation of a study's contribution to the combined effect of the preceding research. It accrues evidence, gradually adding studies one at a time and provides updated estimates ...

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