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Browsing by Subject "Multiple sclerosis"

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    • Conference Object  

      AM-FM texture image analysis in brain white matter lesions in the progression of multiple sclerosis 

      Loizou, Christos P.; Murray, V.; Pattichis, Marios S.; Pantzaris, Marios C.; Pattichis, Constantinos S. (2010)
      We present the use of multiscale Amplitude Modulation Frequency Modulation (AM-FM) methods for analyzing brain white matter lesions that are associated with disease progression. We analyze lesions and normal appearing white ...

    • Conference Object  

      AM-FM texture image analysis in multiple sclerosis brain white matter lesions 

      Loizou, Christos P.; Murray, V.; Pattichis, Marios S.; Pantzaris, Marios C.; Seimenis, Ioannis; Pattichis, Constantinos S. (2010)
      In this study we investigate the use of multiscale Amplitude Modulation-Frequency Modulation (AM-FM) methods for analyzing brain white matter lesions that are associated with multiple sclerosis MRI lesions imaged at 0 and ...

    • Conference Object  

      Brain MR image normalization in texture analysis of multiple sclerosis 

      Loizou, Christos P.; Pantzaris, Marios C.; Seimenis, Ioannis; Pattichis, Constantinos S. (2009)
      A problem that occurs in texture analysis and quantitative analysis of magnetic resonance imaging (MRI), is that the extracted results are not comparable between consecutive or repeated scans or, within the same scan, ...

    • Article  

      Cancer specific risk in multiple sclerosis patients 

      Kyritsis, A. P.; Boussios, Stergios; Pavlidis, Nicholas (2016)
      Multiple sclerosis (MS) is a chronic central nervous system (CNS) autoimmune disease. Studies of cancer risk in MS patients have shown inconsistent findings. A pubmed search of the literature on cancer risk in patients ...

    • Article  

      Chlamydia pneumoniae infection and the risk of multiple sclerosis: A meta-analysis 

      Bagos, Pantelis G.; Nikolopoulos, Georgios K.; Ioannidis, A. (2006)
      We conducted a meta-analysis of studies comparing the presence of Chlamydia pneumoniae (Cpn) between multiple sclerosis (MS) patients and other neurological diseases patients or healthy controls. We identified 26 studies ...

    • Conference Object  

      Clustering subjects in genetic studies with self organizing maps 

      Aristodimou, Aristos; Antoniades, Athos; Pattichis, Constantinos S. (2012)
      Several machine learning techniques have been applied for finding multi-loci associations among Single Nucleotide Polymorphisms (SNPs) and a disease. In this paper it is investigated whether Self Organizing Maps (SOMs) can ...

    • Article  

      Cytokine gene polymorphisms in multiple sclerosis: A meta-analysis of 45 studies including 7379 cases and 8131 controls 

      Nikolopoulos, Georgios K.; Masgala, Aikaterini; Tsiara, Chrissa G.; Limitsiou, O. K.; Karnaouri, Anthi C.; Dimou, Niki L.; Bagos, Pantelis G. (2011)
      Many environmental and genetic factors have been implicated in the development of multiple sclerosis. However, the aetiology has not been clarified yet. Therefore, using a meta-analytic approach, we tried to probe the ...

    • Conference Object  

      Design and development of a haptic peg-board exercise for the rehabilitation of people with multiple sclerosis 

      Xydas, E. G.; Louca, Loucas S. (Affiliation: Mechanical and Manufacturing Engineering Department, University of Cyprus, P.O. Box: 20537, Nicosia, CyprusAffiliation: Mechanical and Manufacturing Engineering Department, University of CyprusCorrespondence Address: Xydas, E. G.Mechanical and Manufacturing Engineering Department, University of Cyprus, P.O. Box: 20537, Nicosia, Cyprusemail: mep4ex01@ucy.ac.cy, 2007)
      Peg-in-Hole methods, like the Nine Hole Peg-Board Test (NHPT) and the Perdue board are widely employed for the functional assessment and therapy of the upper limbs of people with Multiple Sclerosis (MS). Such passive devices ...

    • Article  

      Guest editorial introduction to the special issue on citizen centered e-health systems in a global healthcare environment: Selected papers from ITAB 2009 

      Pattichis, Constantinos S.; Schizas, Christos N.; Kyriacou, Efthyvoulos C.; Fotiadis, Dimitrios Ioannis; Pattichis, Marios S.; Bamidis, Panagiotis D. (2011)
      The January 2011 Special Issue of IEEE Transactions on Information Technology in Biomedicine includes selected papers from Information Technology in Biomedicine (ITAB 2009), held in the month of October in Cyprus. The ...

    • Doctoral Thesis  Open Access

      A haptic-interface based system for the upper-limb rehabilitation of people with multiple sclerosis 

      Xydas, Evagoras G. (Πανεπιστήμιο Κύπρου, Πολυτεχνική Σχολή / University of Cyprus, Faculty of Engineering, 2011-05)
      Για να παρέχει πλήρη και εξειδικευμένη θεραπεία για τα άτομα με πολύπλοκες νευρολογικές βλάβες, όπως είναι τα άτομα με ΣΚΠ, ένα σύστημα αποκατάστασης θα μπορούσε να εκμεταλλεύεται την ικανότητα των ρομποτικών συστημάτων ...

    • Conference Object  

      Identification of kinematic traits in 3D reaching Tasks with the use of a haptic Nine-Hole Peg-Board Test: Comparison between healthy people and people with Multiple Sclerosis 

      Xydas, E. G.; Louca, Loucas S. (Affiliation: Mechanical and Manufacturing Engineering Department, University of Cyprus, P.O. Box: 20537, Nicosia, CyprusAffiliation: Mechanical and Manufacturing Engineering Department, University of Cyprus, CyprusCorrespondence Address: Xydas, E. G.Mechanical and Manufacturing Engineering Department, University of Cyprus, P.O. Box: 20537, Nicosia, Cyprusemail: mep4ex01@ucy.ac.cy, 2008)
      Multiple Sclerosis (MS) is a complex neurological disease that destroys the myelin sheath of the nerves, consequently affecting the motor control ability of the person in numerous ways. Rehabilitation of the upper limb ...

    • Article  

      Meta-analysis of family-based and case-control genetic association studies that use the same cases 

      Bagos, Pantelis G.; Dimou, Niki L.; Liakopoulos, Theodore D.; Nikolopoulos, Georgios K. (2011)
      In many cases in genetic epidemiology, the investigators in an effort to control for different sources of confounding and simultaneously to increase the power perform a family-based and a population-based case-control study ...

    • Article  

      Multiscale amplitude-modulation frequency-modulation (AMFM) texture analysis of multiple sclerosis in brain MRI images 

      Loizou, Christos P.; Murray, V.; Pattichis, Marios S.; Seimenis, Ioannis; Pantzaris, Marios C.; Pattichis, Constantinos S. (2011)
      This study introduces the use of multiscale amplitude modulation-frequency modulation (AM-FM) texture analysis of multiple sclerosis (MS) using magnetic resonance (MR) images from brain. Clinically, there is interest in ...

    • Article  

      No evidence for association of CTLA-4 gene polymorphisms with the risk of developing multiple sclerosis: A meta-analysis 

      Bagos, Pantelis G.; Karnaouri, Anthi C.; Nikolopoulos, Georgios K.; Hamodrakas, Stavros J. (2007)
      We conducted a meta-analysis concerning the association of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) gene polymorphisms with the risk of developing multiple sclerosis (MS). We identified 18 eligible studies ...

    • Conference Object  

      Quantitative analysis of brain white matter lesions in multiple sclerosis subjects 

      Loizou, Christos P.; Pattichis, Constantinos S.; Seimenis, Ioannis; Pantzaris, Marios C. (2009)
      In this study the value of magnetic resonance image (MRI) shape and texture analysis was assessed in multiple sclerosis (MS) subjects, both in differentiating between normal or normal appearing and abnormal tissue and in ...

    • Conference Object  

      Quantitative analysis of brain white matter lesions in multiple sclerosis subjects: Preliminary findings 

      Loizou, Christos P.; Pattichis, Constantinos S.; Seimenis, Ioannis; Eracleous, Eleni A.; Schizas, Christos N.; Pantzaris, Marios C. (2008)
      In this study the value of magnetic resonance image (MRI) shape and texture analysis was assessed in multiple sclerosis (MS) subjects, both in differentiating between normal and abnormal tissue and in assessing disease ...

    • Article  

      Quantitative texture analysis of brain white matter lesions derived from T2-weighted MR images in MS patients with clinically isolated syndrome 

      Loizou, Christos P.; Petroudi, Styliani; Seimenis, Ioannis; Pantzaris, Marios C.; Pattichis, Constantinos S. (2015)
      Introduction: This study investigates the application of texture analysis methods on brain T2-white matter lesions detected with magnetic resonance imaging (MRI) for the prognosis of future disability in subjects diagnosed ...

    • Article  

      Robotic rehabilitation of people with multiple sclerosis with the use of a haptic nine-hole pegboard test 

      Xydas, E. G.; Louca, Loucas S. (2012)
      Multiple Sclerosis (MS) is a complex neurological disease that destroys the myelin sheath of the nerves, consequently affecting the motor control ability in numerous ways. It has been shown that people with MS have the ...

    • Conference Object  

      Texture image analysis of normal appearing white matter areas in Clinically Isolated Syndrome that evolved in demyelinating lesions in subsequent MRI scans: Multiple sclerosis disease evolution 

      Loizou, Christos P.; Seimenis, Ioannis; Pantzaris, Marios C.; Kasparis, Takis; Kyriacou, Efthyvoulos C.; Pattichis, Constantinos S. (2010)
      The purpose of this paper is to explore the use of texture features analysis for evaluating normal appearing white matter (NA WM) areas in brain Magnetic Resonance Imaging (MRI) scans of patients with a first demyelinating ...

    • Conference Object  

      Upper limb assessment of people with multiple sclerosis with the use of a haptic nine hole peg-board test 

      Xydas, E. G.; Louca, Loucas S. (Affiliation: Department of Mechanical and Manufacturing Engineering, University of Cyprus, CyprusCorrespondence Address: Xydas, E. G.Department of Mechanical and Manufacturing Engineering, University of CyprusCyprus, 2009)
      In this work, a nine-hole peg-board test (NHPT) arrangement is implemented in a Virtual Environment with the use of a Haptic Interface that has the form of a small robotic arm. The Haptic NHPT is used as a mean for ...

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