Browsing by Subject "Nanoparticles"

Article

Cationic nanoparticles have superior transvascular flux into solid tumors: Insights from a mathematical model

Stylianopoulos, T.; Soteriou, K.; Fukumura, D.; Jain, R. K. (2013)

Despite their great promise, only a few nanoparticle formulations have been approved for clinical use in oncology. The failure of nano-scale drugs to enhance cancer therapy is in large part due to inefficient delivery. To ...

Article

Continuum model for the phase behavior, microstructure, and rheology of unentangled polymer nanocomposite melts

Stephanou, Pavlos S.; Mavrantzas, V. G.; Georgiou, Georgios C. (2014)

We introduce a continuum model for polymer melts filled with nanoparticles capable of describing in a unified and self-consistent way their microstructure, phase behavior, and rheology in both the linear and nonlinear ...

Article

Controlled production of ZnO nanoparticles from zinc glycerolate in a sol-gel silica matrix

Moleski, R.; Leontidis, Epameinondas; Krumeich, F. (2006)

The controlled production of ZnO nanoparticles within an amorphous silica matrix is achieved using a new methodology consisting of four stages. First, precursor zinc glycerolate nanoparticles are produced within reversed ...

Article

Delivering nanomedicine to solid tumors

Jain, R. K.; Stylianopoulos, T. (2010)

Recent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. While the enhanced permeability and retention effect has served as a key rationale for using nanoparticles to treat ...

Article

Design considerations for nanotherapeutics in oncology

Stylianopoulos, T.; Jain, R. K. (2015)

Nanotherapeutics have improved the quality of life of cancer patients, primarily by reducing the adverse effects of chemotherapeutic agents, but improvements in overall survival are modest. This is in large part due to the ...

Conference Object

Design rules for cancer nanomedicines

Stylianopoulos, T.; Soteriou, K.; Fukumura, D.; Jain, R. K. (Affiliation: Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, CyprusAffiliation: Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United StatesCorrespondence Address: Stylianopoulos, T.Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus, 2012)

The use of nanotechnology has offered new hope for cancer detection, prevention and treatment. Nanoparticle formulations are advantageous over conventional chemotherapy because they can incorporate multiple diagnostic and ...

Article

Drug delivery innovations for enhancing the anticancer potential of vitamin e isoforms and their derivatives

Neophytou, Christiana M.; Constantinou, Andreas I. (2015)

Vitamin E isoforms have been extensively studied for their anticancer properties. Novel drug delivery systems (DDS) that include liposomes, nanoparticles, and micelles are actively being developed to improve Vitamin E ...

Article

The effect of La3+, Ti4+ and Zr4+ dopants on the mechanism of WGS on ceria-doped supported Pt catalysts

Petallidou, Klito C.; Kalamaras, Christos M.; Efstathiou, Angelos M. (2014)

Platinum nanoparticles supported on single CeO2 and TiO 2 metal oxides and Ce0.8Ti0.2O 2-δ solid solution were prepared to investigate the effect of Ti4+-doping of ceria on important mechanistic and kinetic aspects of the ...

Article

The effect of La3+-doping of CeO2 support on the water-gas shift reaction mechanism and kinetics over Pt/Ce1-xLaxO2-δ

Kalamaras, Christos M.; Petallidou, Klito C.; Efstathiou, Angelos M. (2013)

Platinum nanoparticles (dPt=1.0-1.2nm) supported on single CeO2 and La2O3 metal oxides and Ce0.8La0.2O2-δ solid solution were prepared to investigate for the first time the effect of La3+-doping of ceria on important ...

Doctoral Thesis Open Access

Electronic particle manipulation : numerical simulation and device design

Loucaides, Neophytos (Πανεπιστήμιο Κύπρου, Πολυτεχνική Σχολή / University of Cyprus, Faculty of Engineering, 2009-09)

Αυτή η Διατριβή ασχολείται με την προσομοίωση συσκευών οι οποίες χρησιμοποιούν τεχνικές Ηλεκτροκινητικής Εναλλασσόμενου Ρεύματος (ΗΕΡ) για τη διαχείριση μικρο- και νανο-σωματιδίων. Οι προσομοιώσεις αυτές είναι αναγκαίες ...

Article

EPR-effect: Utilizing size-dependent nanoparticle delivery to solid tumors

Stylianopoulos, T. (2013)

Article

Evaluation of electrospun polymer-Fe3O4 nanocomposite mats in malachite green adsorption

Savva, I.; Marinica, O.; Papatryfonos, C. A.; Vekas, L.; Krasia-Christoforou, T. (2015)

Magnetoactive nanocomposite fibers, based on poly(ethylene oxide) (PEO), poly(l-lactide) (PLLA) and pre-formed oleic acid-coated magnetite nanoparticles (OA·Fe3O4), were fabricated by electrospinning and evaluated for the ...

Article

Fabrication and characterization of magnetoresponsive electrospun nanocomposite membranes based on methacrylic random copolymers and magnetite nanoparticles

Savva, I.; Krekos, G.; Taculescu, A.; Marinica, O.; Vekas, L.; Krasia-Christoforou, T. (2012)

Magnetoresponsive polymer-based fibrous nanocomposites belonging to the broad category of stimuli-responsive materials, is a relatively new class of soft composite materials, consisting of magnetic nanoparticles embedded ...

Article

Fabrication and characterization of superparamagnetic and thermoresponsive hydrogels based on oleic-acid-coated Fe3O4 nanoparticles, hexa(ethylene glycol) methyl ether methacrylate and 2-(acetoacetoxy)ethyl methacrylate

Papaphilippou, P.; Pourgouris, A.; Marinica, O.; Taculescu, A.; Athanasopoulos, G. I.; Vekas, L.; Krasia-Christoforou, T. (2011)

Stimuli-responsive hydrogel nanocomposites comprised of swollen polymer networks, in which magnetic nanoparticles are embedded, are a relatively new class of "smart" soft materials presenting a significant impact on various ...

Article

Fabrication and characterization of superparamagnetic poly(vinyl pyrrolidone)/poly(L-lactide)/Fe3O4 electrospun membranes

Savva, I.; Constantinou, D.; Marinica, O.; Vasile, E.; Vekas, L.; Krasia-Christoforou, T. (2014)

The fabrication of magnetoactive fibrous nanocomposite membranes based on poly(vinyl pyrrolidone) (PVP), poly(L-lactide) (PLLA) and pre-formed oleic acid coated magnetite nanoparticles (OA Fe3O4) is presented. The ...

Article

Fabrication, characterization and applications of novel nanoheater structures

Gu, Z.; Cui, Q.; Chen, J.; Buckley, J.; Ando, T.; Erdeniz, D.; Wong, P.; Hadjiafxenti, A.; Epaminonda, P.; Gunduz, I. E.; Rebholz, Claus; Doumanidis, C. C. (2013)

Nanoheaters are reactive nanostructures that can generate localized heat through controlled ignition. Besides the widely used nanofoil structure with multiple alternative Al-Ni layers, various new nanostructures have been ...

Article

Fabrication, characterization, and evaluation in drug release properties of magnetoactive poly(ethylene oxide)-poly(l -lactide) electrospun membranes

Savva, I.; Odysseos, A. D.; Evaggelou, L.; Marinica, O.; Vasile, E.; Vekas, L.; Sarigiannis, Y.; Krasia-Christoforou, T. (2013)

The fabrication of electrospun magnetoactive fibrous nanocomposite membranes based on the water-soluble and biocompatible poly(ethylene oxide) (PEO), the biocompatible and biodegradable poly(l-lactide) (PLLA) and preformed ...

Article

Formation mechanism of nanotubes comprising layers of PbS nanoparticles in polymer-surfactant solutions

Orphanou, M.; Leontidis, Epameinondas; Kyprianidou-Leodidou, Tasoula; Caseri, Walter; Krumeich, F.; Kyriacou, Kyriacos C. (2006)

The crystallization of PbS in aqueous solutions containing the surfactant sodium dodecyl sulfate (SDS) and hydrophilic polymers resulted in a novel type of metastable nanotubes, the walls of which consist of layers of ...

Article

Heterogeneity in nanocomposite hydrogels from poly(ethylene oxide) cross-linked with silicate nanoparticles

Schexnailder, P.; Loizou, Elena; Porcar, L.; Butler, P.; Schmidt, G. (2009)

We investigate the influence of ionic strength on the structural heterogeneity and viscoelastic properties of nanocomposite hydrogels. We use small-angle scattering and rheology to monitor structural changes as a function ...

Article

High-resolution whole-mount in situ hybridization using quantum dot nanocrystals

Ioannou, Androulla; Eleftheriou, Iro; Lubatti, Andrea; Charalambous, Anna; Skourides, Paris A. (2012)

The photostability and narrow emission spectra of nanometer-scale semiconductor crystallites (QDs) make them desirable candidates for whole-mount fluorescent in situ hybridization to detect mRNA transcripts in morphologically ...