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Browsing by Subject "Neoplasms"

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    • Article  

      Adjuvant Cytotoxic and Endocrine Therapy in Pre- and Postmenopausal Patients with Breast Cancer and One to Nine Infiltrated Nodes: Five-Year Results of the Hellenic Cooperative Oncology Group Randomized HE 10/92 Study 

      Fountzilas, George; Stathopoulos, G. P.; Kouvatseas, G.; Polychronis, A.; Klouvas, G. D.; Samantas, E.; Zamboglou, N.; Kyriakou, K.; Adamou, A.; Pectasides, Dimitrios; Economopoulos, T.; Kalofonos, H. P.; Bafaloukos, Dimitrios; Georgoulias, V.; Razi, E. D.; Koukouras, D.; Zombolas, V.; Kosmidis, Paraskevas A.; Skarlos, Dimosthenis V.; Pavlidis, Nicholas (2004)
      The present randomized phase III trial was designed to detect a 15% benefit in relapse-free survival (RFS) or overall survival (OS) from the incorporation of adjuvant tamoxifen to the combination of CNF [cyclophosphamide, ...

    • Article  

      Age-Dependent Metastatic Spread and Survival: Cancer of Unknown Primary as a Model 

      Hemminki, K.; Pavlidis, Nicholas; Tsilidis, K. K.; Sundquist, K.; Ji, J. (2016)
      In order to describe a novel approach for the clinical study of metastases, we provide here age-specific incidence and survival data for cancer of unknown primary (CUP). Metastases in various organs are found at CUP ...

    • Article  

      Angiogenesis in cancer of unknown primary: Clinicopathological study of CD34, VEGF and TSP-1 

      Karavasilis, V.; Malamou-Mitsi, Vassiliki D.; Briassoulis, E. Ch; Tsanou, E.; Kitsou, E.; Kalofonos, H. P.; Fountzilas, George; Fotsis, T.; Pavlidis, Nicholas (2005)
      Background: Cancer of unknown primary remains a mallignancy of elusive biology and grim prognosis that lacks effective therapeutic options. We investigated angiogenesis in cancer of unknown primary to expand our knowledge ...

    • Article  

      Axillary nodal metastases from carcinoma of unknown primary (CUPAx): A systematic review of published evidence 

      Pentheroudakis, George; Lazaridis, G.; Pavlidis, Nicholas (2010)
      Axillary lymph node metastases from adenocarcinoma or poorly differentiated carcinoma of unknown primary (CUPAx) represent a rare clinical entity without consensus on its biology, management and outcome. We systematically ...

    • Article  

      Brain metastasis of unknown primary: A diagnostic and therapeutic dilemma 

      Polyzoidis, K. S.; Miliaras, G.; Pavlidis, Nicholas (2005)
      The diagnosis of a brain metastasis is usually made during the routine follow up examinations of patients with known cancer, who are under the care of oncology departments. The involvement of the neurosurgeon depends on ...

    • Article  

      Cancer and pregnancy 

      Pavlidis, Nicholas (2000)

    • Article  

      Cancer and pregnancy: A comprehensive review 

      Voulgaris, E.; Pentheroudakis, George; Pavlidis, Nicholas (2011)
      Background: Pregnancy complicated by cancer is relatively rare but, as women in western societies tend to delay childbearing to the third and fourth decade of life, this phenomenon is going to be encountered more often in ...

    • Article  

      Cancer and pregnancy: What should we know about the management with systemic treatment of pregnant women with cancer? 

      Pavlidis, Nicholas (2011)
      The incidence of cancer during pregnancy is a rare phenomenon and is estimated to occur in 1:1000 pregnancies. This co-existence is likely to rise since the delay of childbearing to the later reproductive age is nowadays ...

    • Article  

      Cancer diagnosis in a cohort of patients with Sjogren's syndrome and rheumatoid arthritis: A single-center experience and review of the literature 

      Boussios, Stergios; Pentheroudakis, George; Somarakis, G.; Markatseli, T. E.; Drosos, Alexandros A.; Pavlidis, Nicholas (2014)
      Background: With the development of modern therapies and better care of patients with autoimmune rheumatic diseases (ARDs) increased survival has been achieved. However, ARDs may share an association with risk of lymphomas ...

    • Article  

      Cancer of unknown primary during pregnancy: An exceptionally rare coexistence 

      Pavlidis, Nicholas; Peccatori, Fedro A.; Lofts, F.; Greco, F. A. (2015)
      Background: Cancer in pregnancy is a rare disease with breast cancer, cervical cancer, melanoma and Hodgkin's disease to be the most commonly diagnosed malignancies during gestation. Cancer of unknown primary (CUP) is a ...

    • Article  

      Cancer of Unknown Primary origin in the genomic era: Elucidating the dark box of cancer 

      Economopoulou, P.; Mountzios, G.; Pavlidis, Nicholas; Pentheroudakis, George (2015)
      Cancer of Unknown Primary (CUP) comprises a heterogeneous disease group with diagnosis of metastatic malignancy in the absence of an identifiable primary site after diagnostic work up. CUP may either resemble a specific ...

    • Article  

      Cancer of unknown primary patients with midline nodal distribution: Midway between poor and favourable prognosis? 

      Pentheroudakis, George; Stoyianni, A.; Pavlidis, Nicholas (2011)
      Background: Midline nodal cancer of unknown primary (CUP) has varying definitions and an unclear natural history compared to that of extragonadal germ cell cancer (EGCC) and neuroendocrine tumors. Methods: We systematically ...

    • Article  

      Cancer of unknown primary site 

      Pavlidis, Nicholas; Pentheroudakis, George (2012)
      Cancer of unknown primary site (CUP) is a well recognised clinical disorder, accounting for 3-5 of all malignant epithelial tumours. CUP is clinically characterised as an aggressive disease with early dissemination. ...

    • Article  

      Cancer of unknown primary site: 20 questions to be answered 

      Pavlidis, Nicholas; Pentheroudakis, George (2010)
      Cancer of unknown primary (CUP) is a common, well-recognized and heterogeneous clinical syndrome. Patients with CUP present with metastatic disease in the absence of an identifiable primary tumour despite a diagnostic ...

    • Article  

      Cancer of unknown primary site: Missing primary or missing biology? 

      Pentheroudakis, George; Briassoulis, E. Ch; Pavlidis, Nicholas (2007)
      Cancer of unknown primary site (CUP) ranks as the fourth most common cause of cancer deaths and represents both a diagnostic and a management challenge. In CUP, the regression or dormancy of the primary tumor, the development ...

    • Article  

      Cancer of unknown primary: Biological and clinical characteristics 

      Pavlidis, Nicholas (2003)

    • Article  

      Cancer of unknown primary: What kind of chemotherapy? what kind of disease? 

      Pentheroudakis, George; Pavlidis, Nicholas (2009)

    • Article  

      Cancer prevalence and mortality in centenarians: A systematic review 

      Pavlidis, Nicholas; Stanta, G.; Audisio, R. A. (2012)
      Life expectancy has dramatically expanded, the global population has aged unprecedentedly and the number of centenarians has significantly increased. The analysis of autopsy series, cancer registries data, vital statistics ...

    • Article  

      Cancer specific risk in multiple sclerosis patients 

      Kyritsis, A. P.; Boussios, Stergios; Pavlidis, Nicholas (2016)
      Multiple sclerosis (MS) is a chronic central nervous system (CNS) autoimmune disease. Studies of cancer risk in MS patients have shown inconsistent findings. A pubmed search of the literature on cancer risk in patients ...

    • Article  

      Cancer treatment reviews welcomes submission of the Cochrane Reviews 

      Pavlidis, Nicholas; Stahel, R. A.; Clarke, M.; Djulbegovic, B. (2006)

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