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Browsing by Subject "Neuroendocrine tumor"

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    • Article  

      Cancer of unknown primary patients with midline nodal distribution: Midway between poor and favourable prognosis? 

      Pentheroudakis, George; Stoyianni, A.; Pavlidis, Nicholas (2011)
      Background: Midline nodal cancer of unknown primary (CUP) has varying definitions and an unclear natural history compared to that of extragonadal germ cell cancer (EGCC) and neuroendocrine tumors. Methods: We systematically ...

    • Article  

      Cancer of unknown primary site 

      Pavlidis, Nicholas; Pentheroudakis, George (2012)
      Cancer of unknown primary site (CUP) is a well recognised clinical disorder, accounting for 3-5 of all malignant epithelial tumours. CUP is clinically characterised as an aggressive disease with early dissemination. ...

    • Article  

      Cancer of unknown primary site: 20 questions to be answered 

      Pavlidis, Nicholas; Pentheroudakis, George (2010)
      Cancer of unknown primary (CUP) is a common, well-recognized and heterogeneous clinical syndrome. Patients with CUP present with metastatic disease in the absence of an identifiable primary tumour despite a diagnostic ...

    • Article  

      Cancer of unknown primary: Biological and clinical characteristics 

      Pavlidis, Nicholas (2003)

    • Article  

      Cancers of unknown primary site: ESMO clinical practice guidelines for diagnosis, treatment and follow-up 

      Pavlidis, Nicholas; Briassoulis, E. Ch; Pentheroudakis, George (2010)

    • Article  

      Cancers of unknown primary site: ESMO clinical recommendations for diagnosis, treatment and follow-up 

      Briassoulis, E. Ch; Pavlidis, Nicholas; Felip, E. (2009)

    • Article  

      Diagnostic and therapeutic management of cancer of an unknown primary 

      Pavlidis, Nicholas; Briassoulis, E. Ch; Hainsworth, J.; Greco, F. A. (2003)
      Metastatic Cancer of Unknown Primary Site (CUP) accounts for approximately 3% of all malignant neoplasms and is therefore one of the 10 most frequent cancer diagnoses in man. Patients with CUP present with metastatic disease ...

    • Article  

      Forty years experience of treating cancer of unknown primary 

      Pavlidis, Nicholas (2007)
      Cancer of unknown primary site (CUP) is not a rare tumour. It accounts as the seventh to eighth most frequently diagnosed cancer in a general medical oncology service. Since CUP is not a homogeneous disease and it consists ...

    • Article  

      Long-term survivors among patients with cancer of unknown primary 

      Pavlidis, Nicholas; Petrakis, Dimitrios; Golfinopoulos, Vassilis; Pentheroudakis, George (2012)
      There is a general conception among oncologists that CUP patients behave poorly to treatment and carry a dismal survival. In this paper we are trying to elucidate the different groups of CUP patients and to describe in ...

    • Article  

      Neuroendocrine carcinoma of unknown primary: A systematic review of the literature and a comparative study with other neuroendocrine tumors 

      Stoyianni, A.; Pentheroudakis, George; Pavlidis, Nicholas (2011)
      Introduction: Neuroendocrine carcinomas of unknown primary (NCUP) represent a specific subset with relatively favorable prognosis. Data on biology, management and outcome of NCUP patients have not been systematically ...

    • Article  

      Neuroendocrine Merkel cell nodal carcinoma of unknown primary site: Management and outcomes of a rare entity 

      Kotteas, E. A.; Pavlidis, Nicholas (2015)
      Merkel cell nodal carcinoma of unknown primary (MCCUP) is a rare neuroendocrine tumour with distinct clinical and biological behaviour. We conducted a review of retrospective data extracted from 90 patients focusing on the ...

    • Article  

      Optimal therapeutic management of patients with distinct clinicopathological cancer of unknown primary subsets 

      Pavlidis, Nicholas (2012)
      Cancer of unknown primary sites (CUP) is a compilation of various malignant entities-the majority of which behave aggressively and carry poor prognosis. CUP is classified into two different clinicopathological groups: the ...

    • Article  

      A patient with neuroendocrine carcinoma of the urinary bladder and paraneoplastic degenerative parencephalitis: A case report and review of the literature 

      Fotopoulos, George; Pentheroudakis, George; Ioachim, E.; Pavlidis, Nicholas (2014)
      Neuroendocrine carcinomas of the bladder (small cell, large cell, typical and atypical carcinoids) are rare and usually co exist with urothelial carcinoma. As in small cell carcinoma of the lung, various paraneoplastic ...

    • Article  

      Probing the unknown in cancer of unknown primary: Which way is the right way? 

      Pentheroudakis, George; Pavlidis, Nicholas (2010)

    • Article  

      Prognostic significance of WNT and hedgehog pathway activation markers in cancer of unknown primary 

      Fotopoulos, George; Goussia, Anna; Bareta, E.; Koumpis, E.; Chrisafi, S.; Bobos, M.; Malamou-Mitsi, Vassiliki D.; Fountzilas, George; Pavlidis, Nicholas; Pentheroudakis, George (2015)
      Background: Cancer of unknown primary (CUP) possesses distinct biology and peculiar natural history, in which the roles of the winged and hedgehog signalling pathways are unclear. Materials and methods: We constructed ...

    • Article  

      The value of neuroendocrine markers in non-small cell lung cancer: a comparative immunohistopathologic study 

      Kiriakogiani-Psaropoulou, P.; Malamou-Mitsi, Vassiliki D.; Martinopoulou, U.; Legaki, S.; Tamvakis, N.; Vrettou, E.; Fountzilas, George; Skarlos, Dimosthenis V.; Kosmidis, Paraskevas A.; Pavlidis, Nicholas (1994)
      In order to estimate the value of immunohistochemical identification of neuroendocrine (NE) differentiation markers in non-small cell lung carcinomas (NSCLCs), we investigated the expression of five neuroendocrine and ...

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