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Browsing by Subject "Odds ratio"

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    • Article  

      Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Rapti, E.; Mantzios, Georgios P.; Kapsimali, Violetta; Travlou, Anthi S. (2007)
      The effect of the 675 insertion/deletion (4G/5G) polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene on the risk of venous thromboembolism (VTE) remains controversial. In this study, we performed a meta-analysis ...

    • Article  

      Efficacy and safety of more intensive lowering of LDL cholesterol [1] 

      Bonovas, Stefanos; Nikolopoulos, Georgios K.; Sitaras, N. M. (2011)

    • Article  

      Evaluation of the prognostic role of centromere 17 gain and HER2/topoisomerase II alpha gene status and protein expression in patients with breast cancer treated with anthracycline-containing adjuvant chemotherapy: Pooled analysis of two Hellenic Cooperative Oncology Group (HeCOG) phase III trials 

      Fountzilas, George; Dafni, U.; Bobos, M.; Kotoula, V.; Batistatou, Anna; Xanthakis, I.; Papadimitriou, C.; Kostopoulos, I.; Koletsa, T.; Tsolaki, E.; Televantou, D.; Timotheadou, E.; Koutras, A. K.; Klouvas, G. D.; Samantas, E.; Pisanidis, N.; Karanikiotis, C.; Sfakianaki, I.; Pavlidis, Nicholas; Gogas, H.; Linardou, H.; Kalogeras, K. T.; Pectasides, Dimitrios; Dimopoulos, M. A. (2013)
      Background: The HER2 gene has been established as a valid biological marker for the treatment of breast cancer patients with trastuzumab and probably other agents, such as paclitaxel and anthracyclines. The TOP2A gene has ...

    • Article  

      Fcγ receptor polymorphisms and their association with periodontal disease: A meta-analysis 

      Dimou, Niki L.; Nikolopoulos, Georgios K.; Hamodrakas, Stavros J.; Bagos, Pantelis G. (2010)
      Aim: A systematic review and a meta-analysis were conducted in order to investigate the potential association of Fcγ receptor (FcγR) polymorphisms with susceptibility to aggressive and chronic periodontal disease. Materials ...

    • Article  

      The GNB3 C825T polymorphism and essential hypertension: A meta-analysis of 34 studies including 14 094 cases and 17 760 controls 

      Bagos, Pantelis G.; Elefsinioti, Antigoni L.; Nikolopoulos, Georgios K.; Hamodrakas, Stavros J. (2007)
      OBJECTIVES: The C825T single nucleotide polymorphism of the G-protein β3 (GNB3) has been implicated in susceptibility to essential hypertension, through the expression of an alternatively spliced truncated variant. In an ...

    • Article  

      Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and coronary artery disease: A meta-analysis 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Vaiopoulos, G.; Travlou, Anthi S. (2007)
      Background: The platelet-collagen receptor, glycoprotein (GP) la/lla plays a crucial role in the adhesion of platelets to fibrillar collagen, an event contributing to the pathogenesis of thrombosis. The C807T polymorphism ...

    • Article  

      Multiple-treatments meta-analysis of chemotherapy and targeted therapies in advanced breast cancer 

      Mauri, D.; Polyzos, N. P.; Salanti, G.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2008)
      Background: Many systemic nonhormonal regimens have been evaluated across several hundreds of randomized trials in advanced breast cancer. We aimed to quantify the relative merits of these regimens in prolonging survival. ...

    • Article  

      Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis 

      Mauri, D.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2005)
      Background: Interest in the use of preoperative systemic treatment in the management of breast cancer has increased because such neoadjuvant therapy appears to reduce the extent of local surgery required. We compared the ...

    • Article  

      Phase II study of irinotecan and mitomycin C in 5-fluorouracil-pretreated patients with advanced colorectal and gastric cancer 

      Bamias, A. T.; Papamichael, D.; Syrigos, K.; Pavlidis, Nicholas (2003)
      The aim of this phase II study was to investigate the tolerance and efficacy of a second-line irinotecan/ mitomycin C combination in patients with advanced gastric or colorectal cancer, pretreated with 5-fluorouracil. Forty ...

    • Article  

      Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: Meta-analysis 

      Mauri, D.; Pavlidis, Nicholas; Polyzos, N. P.; Ioannidis, J. P. A. (2006)
      Background: Aromatase inhibitors and inactivators have been extensively tested in patients with advanced breast cancer, but it is unclear whether they offer any survival benefits compared with standard hormonal treatment ...

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