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Browsing by Subject "Oligopeptides"

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    • Article  

      Analgesic tolerance and cross-tolerance to i.c.v. endomorphin-1, endomorphin-2, and morphine in mice; 15276249 

      Soignier, R. D.; Vaccarino, A. L.; Fanti, Kostas A.; Wilson, A. M.; Zadina, J. E. (2004)
      The present study examined the development of analgesic tolerance to endomorphin-1 (EM1), endomorphin-2 (EM2), and morphine, and cross-tolerance among these drugs. Male Swiss Webster mice were injected i.c.v. with EM1, ...

    • Doctoral Thesis  Open Access

      Computational study of ionic effects on the conformational stability and the helix/coil equilibrium of model oligopeptides 

      Ioannou, Filippos D. (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2013-01)
      Η παρούσα διδακτορική διατριβή είναι μια υπολογιστική μελέτη της επίδρασης των αλάτων στη στερεοδιαταξική σταθερότητα και την ισορροπία έλικας/τυχαίου σπειρώματος ολιγοπεπτιδίων, με στόχο τη διαφώτιση του μηχανισμού της ...

    • Article  

      In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury 

      Constantinou, Constantina; Apidianakis, Yiorgos; Psychogios, N.; Righi, V.; Mindrinos, M. N.; Khan, N.; Swartz, H. M.; Szeto, H. H.; Tompkins, R. G.; Rahme, L. G.; Aria Tzika, A. (2016)
      Trauma is the most common cause of mortality among individuals aged between 1 and 44 years and the third leading cause of mortality overall in the US. In this study, we examined the effects of trauma on the expression of ...

    • Article  

      Phase II study of LU 103793 (dolastatin analogue) in patients with metastatic breast cancer 

      Kerbrat, P.; Dieras, V.; Pavlidis, Nicholas; Ravaud, A.; Wanders, J.; Fumoleau, P. (2003)
      LU 103793 is a synthetic analogue of Dolastatin 15 that inhibits tubulin polymerisation. The aim of this study was to evaluate the efficacy and tolerability of LU 103793 in patients with metastatic breast cancer who had ...

    • Article  

      Self-assembly of an aspartate-rich sequence from the adenovirus fiber shaft: Insights from molecular dynamics simulations and experiments 

      Tamamis, Phanourios; Terzaki, K.; Kassinopoulos, Marios; Mastrogiannis, L.; Mossou, E.; Forsyth, V. T.; Mitchell, E. P.; Mitraki, A.; Archontis, Georgios Z. (2014)
      The self-assembly of short peptides into fibrous nanostructures (such as fibrils and tubes) has recently become the subject of intense theoretical and experimental scrutiny, as such assemblies are promising candidates for ...

    • Article  

      Self-assembly of phenylalanine oligopeptides: Insights from experiments and simulations 

      Tamamis, Phanourios; Adler-Abramovich, L.; Reches, M.; Marshall, K.; Sikorski, P.; Serpell, L.; Gazit, E.; Archontis, Georgios Z. (2009)
      Studies of peptide-based nanostructures provide general insights into biomolecular self-assembly and can lead material engineering toward technological applications. The diphenylalanine peptide (FF) self-assembles into ...

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