Browsing by Subject "Pathophysiology"
Now showing items 1-12 of 12
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Article
The beginning of personalized medicine in sepsis: Small steps to a bright future
(2014)There is a growing recognition that there is a need for a more personalized approach towards sepsis care. In most clinical trials investigating novel therapeutic interventions against sepsis, patients have been considered ...
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Article
The better of two evils? Evidence that children exhibiting continuous conduct problems high or low on callous-unemotional traits score on opposite directions on physiological and behavioral measures of fear
(Cambridge University Press, 2015)The present study examines whether heterogeneous groups of children identified based on their longitudinal scores on conduct problems (CP) and callous-unemotional (CU) traits differ on physiological and behavioral measures ...
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Article
Cancer of unknown primary site
(2012)Cancer of unknown primary site (CUP) is a well recognised clinical disorder, accounting for 3-5 of all malignant epithelial tumours. CUP is clinically characterised as an aggressive disease with early dissemination. ...
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Article
Clinical expression of autoimmune hepatitis in a Nine-Year-Old Girl with visceral leishmaniasis
(2011)Autoimmune hepatitis (AIH) is a chronic disease of unknown aetiology, which usually progresses to cirrhosis if not diagnosed and treated promptly. In childhood, autoimmune hepatitis prevalently presents with non-specific ...
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Article
Immunomodulatory therapy for sepsis: An update
(2011)Currently the treatment mainstay of sepsis is early and appropriate antibiotic therapy, accompanied by aggressive fluid administration, the use of vasopressors when needed and the prompt initiation of measures to support ...
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Conference Object
In vivo imaging of microvasculature using optical coherence tomography
(Correspondence Address: Vakoc, B. J., 2010)In vivo imaging technologies drive the development of improved cancer therapies by revealing critical aspects of the complex pathophysiology of solid tumors in small animal models[1]. The abnormal vascular function, which ...
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Article
Is the mortality rate for septic shock really decreasing?
(2008)Survival rates for patients in septic shock have gradually improved in critical care units worldwide over the last 25 years. Further improvement will be predicated on the discovery of new therapies to disrupt the underlying ...
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Article
Noncardiogenic pulmonary edema: An unusual and serious complication of anticancer therapy
(2001)Noncardiogenic pulmonary edema (NCPE) is a rare and less well-recognizable pulmonotoxic syndrome of anticancer therapy than pneumonitis/fibrosis. NCPE is a clinical syndrome characterized by simultaneous presence of severe ...
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Article
Perspectives for targeted therapies in cancer of unknown primary site
(2006)Cancer of unknown primary site (CUP) ranks as the fourth most common cause of cancer deaths. Regression of the primary, early development of systemic metastases and resistance to therapy are hallmarks of this heterogeneous ...
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Article
Positive urinary cytology in patients with lung cancer in the absence of obvious urine tract metastases
(2011)Purpose: To study the phenomenon of positive urine cytology in patients with lung cancer in the absence of obvious urothelial metastases. Patients and methods: 150 patients with small (SCLC) and non-small cell lung cancer ...
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Article
Sense of Coherence and Defense Style Predict Sleep Difficulties in Early Non-metastatic Colorectal Cancer
(2016)Background: Sleep disturbances are common in cancer patients, but little is known about the complex interplay between the background psychological profile, coping with health stressors capacities and psychological distress ...
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Article
Unemotional on all counts: Evidence of reduced affective responses in individuals with high callous-unemotional traits across emotion systems and valences
(Psychology Press Ltd, 2016)The current study aimed to identify atypical neurophysiological activity associated with deficient affective processing in individuals with high callous-unemotional traits (CU). Fifty-six participants (M age = 20.52; 46% ...