Browsing by Subject "Peptides"

Article

Analgesic tolerance and cross-tolerance to i.c.v. endomorphin-1, endomorphin-2, and morphine in mice; 15276249

Soignier, R. D.; Vaccarino, A. L.; Fanti, Kostas A.; Wilson, A. M.; Zadina, J. E. (2004)

The present study examined the development of analgesic tolerance to endomorphin-1 (EM1), endomorphin-2 (EM2), and morphine, and cross-tolerance among these drugs. Male Swiss Webster mice were injected i.c.v. with EM1, ...

Article

Chiral separations using a polypeptide and polymeric dipeptide surfactant polyelectrolyte multilayer coating in open-tubular capillary electrochromatography

Kamande, M. W.; Zhu, X.; Kapnissi‐Christodoulou, Constantina P.; Warner, I. M. (2004)

A polyelectrolyte multilayer (PEM) coating consisting of the polypeptide, poly(L-lysine) hydrobromide, poly(L-lysine) and the polymeric dipeptide surfactant, poly(sodium undecanoyl-L-leutcyl-alaninate), poly(L-SULA), is ...

Doctoral Thesis Open Access

Computational study of ionic effects on the conformational stability and the helix/coil equilibrium of model oligopeptides

Ioannou, Filippos D. (Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2013-01)

Η παρούσα διδακτορική διατριβή είναι μια υπολογιστική μελέτη της επίδρασης των αλάτων στη στερεοδιαταξική σταθερότητα και την ισορροπία έλικας/τυχαίου σπειρώματος ολιγοπεπτιδίων, με στόχο τη διαφώτιση του μηχανισμού της ...

Article

Helix formation by alanine-based peptides in pure water and electrolyte solutions: Insights from molecular dynamics simulations

Ioannou, F.; Leontidis, Epameinondas; Archontis, Georgios Z. (2013)

Specific ion effects on oligopeptide conformations in solution are attracting strong research attention, because of their impact on the protein-folding problem and on several important biological-biotechnological applications. ...

Article

In vivo, site-specific, covalent conjugation of quantum dots to proteins via split-intein splicing

Charalambous, Anna; Andreou, Maria I.; Antoniades, Ioanna; Christodoulou, Neophytos; Skourides, Paris A. (2012)

The ability to target proteins with nanostructures and/or nanodevices in vivo is important for understanding and controlling their biological function. Quantum dots (QDs) serve as an ideal model nanostructure due to their ...

Article

Model investigations for vanadium-protein interactions: Vanadium(III) compounds with dipeptides and their oxovanadium(IV) analogues

Tasiopoulos, Anastasios J.; Tolis, Evangelos I.; Tsangaris, John Michael; Evangelou, Angelos M.; Woollins, J. D.; Slawin, A. M. Z.; Pessoa, J. C.; Correia, I.; Kabanos, Themistoklis A. (2002)

The reaction of VCl3 with 1,10-phenanthroline and a series of dipeptides (H2dip), having aliphatic as well as aromatic side chains, in methyl alcohol and in the presence of triethylamine affords vanadium(III) compounds of ...

Article

Models of oxovanadium(IV)-protein interactions: The first oxovanadium(IV) complexes with dipeptides

Tasiopoulos, Anastasios J.; Vlahos, Antonis T.; Keramidas, Anastasios D.; Kabanos, Themistoklis A.; Deligiannakis, Yiannis G.; Raptopoulou, Catherine P.; Terzis, Aris (1996)

Article

Specific antibody to Cryptococcus neoformans glucurunoxylomannan antagonizes antifungal drug action against cryptococcal biofilms in vitro

Martinez, Luis R.; Christaki, Eirini; Casadevall, Arturo (2006)

The fungus Cryptococcus neoformans possesses a polysaccharide capsule and can form biofilms on medical devices. We investigated the efficacy that the combination of a specific antibody to the capsular polysaccharide and ...

Article

Specific interactions of sodium salts with alanine dipeptide and tetrapeptide in water: Insights from molecular dynamics

Ioannou, F.; Archontis, Georgios Z.; Leontidis, Epameinondas (2011)

We examine computationally the dipeptide and tetrapeptide of alanine in pure water and solutions of sodium chloride (NaCl) and iodide (NaI), with salt concentrations up to 3 M. Enhanced sampling of the configuration space ...

Article

Synthetic analogs for oxovanadium(IV/V)-glutathione interaction: An NMR, EPR, synthetic and structural study of oxovanadium(IV/V) compounds with sulfhydryl-containing pseudopeptides and dipeptides

Tasiopoulos, Anastasios J.; Troganis, Anastassios N.; Deligiannakis, Yiannis G.; Evangelou, Angelos M.; Kabanos, Themistoklis A.; Woollins, J. D.; Slawin, A. (2000)

The reaction of [VO(CH3COO)2(phen)] (phen = 1,10-phenanthroline) with the sulfhydryl-containing pseudopeptides (scp), N-(2-mercaptopropionyl)glycine (H3mpg), N-(2-mercaptopropionyl)cysteine (H4m2pc), N-(3-mercaptopropion ...

Article

UV resonance Raman study of TTR(105-115) structural evolution as a function of temperature

Pieridou, Galatia K.; Avgousti-Menelaou, C.; Tamamis, Phanourios; Archontis, Georgios Z.; Hayes, Sophia C. (2011)

UV resonance Raman spectroscopy was used to probe the temperature dependence of the conformation of TTR(105-115) in solution. Resonance Raman spectra with excitation at 239.5 nm, show an increase in the absolute resonance ...