Browsing by Subject "Prospective study"

Article

Anxiety, depression and defense mechanisms associated with treatment decisional preferences and quality of life in non-metastatic breast cancer: A 1-year prospective study

Hyphantis, T.; Almyroudi, A.; Paika, V.; Degner, L. F.; Carvalho, A. F.; Pavlidis, Nicholas (2013)

Objective: Treatment decisional preferences impact breast cancer patients' health-related quality of life (HRQoL) and may relate to psychological variables, although many aspects of this relationship remain unknown. This ...

Article

The association of community violence exposure with middle-school achievement: A prospective study

Henrich, Christopher C.; Schwab-Stone, M.; Fanti, Kostas A.; Jones, S. M.; Ruchkin, V. (2004)

This study investigated the long-term effects of exposure to community violence on academic achievement and feelings of safety in school among a large sample of urban middle-school students (N = 759). It also considered ...

Article

The beneficial effect of tamoxifen on serum lipoprotein-a levels: An additional anti-atherogenic property

Elisaf, Moses S.; Bairaktari, Eleni Th; Nikolaides, C.; Fountzilas, George; Tzallas, C. S.; Siamopoulos, K. C.; Tsolas, O.; Pavlidis, Nicholas (1996)

It has recently been suggested that increased lipoprotein (a) levels are an independent risk factor for coronary heart disease. It has also been reported that tamoxifen can induce changes in blood lipid values. In this ...

Article

Combination chemotherapy with cisplatin and/or doxorubicin in malignant mesothelioma. A prospective study

Tsavaris, N.; Primikirios, N.; Mylonakis, N.; Varouchakis, G.; Dosios, T.; Pavlidis, Nicholas; Skarlos, Dimosthenis V.; Tasopoulos, T.; Dritsas, J.; Kosmidis, Paraskevas A. (1997)

From June 1984 to October 1995, forty seven consecutive patients (pts) with a confirmed diagnosis of diffuse malignant mesothelioma (MM) of the pleura (41) and peritoneum (6), were treated with cisplatin (CDDP) (24 pts) ...

Article

Comparative study of prognostic value for coronary disease risk between the U.K. prospective diabetes study and Framingham models: Response to Protopsaltis et al. [9] (multiple letters)

Stevens, R. J.; Holman, R.; Protopsaltis, I. D.; Nikolopoulos, Georgios K.; Melidonis, Andreas (2004)

Article

Diagnostic and therapeutic management of cancer of an unknown primary

Pavlidis, Nicholas; Briassoulis, E. Ch; Hainsworth, J.; Greco, F. A. (2003)

Metastatic Cancer of Unknown Primary Site (CUP) accounts for approximately 3% of all malignant neoplasms and is therefore one of the 10 most frequent cancer diagnoses in man. Patients with CUP present with metastatic disease ...

Conference Object

First and second order statistical texture features in carotid plaque image analysis: Preliminary results from ongoing research

Kyriacou, Efthyvoulos C.; Nicolaïdes, Andrew N.; Pattichis, Constantinos S.; Petroudi, Styliani; Pattichis, Marios S.; Griffin, Maura B.; Kakkos, Stavros K.; Makris, Gregory C. (2011)

Carotid plaques have been associated with ipsilateral neurological symptoms. High-resolution ultrasound can provide information not only on the degree of carotid artery stenosis but also on the characteristics of the ...

Article

Metabolic syndrome and its components as predictors of all-cause mortality and coronary heart disease in type 2 diabetic patients

Protopsaltis, I. D.; Nikolopoulos, Georgios K.; Dimou, Eftihia; Brestas, Paris; Kokkoris, Stelios; Korantzopoulos, Panagiotis; Melidonis, Andreas (2007)

Background: There is no consistent evidence regarding the prognostic value of metabolic syndrome (MS) in predicting all-cause mortality and coronary heart disease (CHD) risk among type 2 diabetic patients. We sought to ...

Article

Paclitaxel (175 mg/m2) plus carboplatin versus paclitaxel (225 mg/m2) plus carboplatin in non-small cell lung cancer: A randomized study

Kosmidis, Paraskevas A.; Mylonakis, N.; Fountzilas, George; Samantas, E.; Athanasiades, A.; Pavlidis, Nicholas; Skarlos, Dimosthenis V. (1997)

A recent phase II study by our group documented a response rate of 27% with the combination paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) 175 mg/m2 plus carboplatin dosed to a target area under the ...

Article

Paclitaxel (175 mg/m2) plus carboplatin versus paclitaxel (225 mg/m2) plus carboplatin in non-small cell lung cancer: a randomized study.

Kosmidis, Paraskevas A.; Mylonakis, N.; Fountzilas, George; Samantas, E.; Athanasiades, A.; Pavlidis, Nicholas; Skarlos, Dimosthenis V. (1997)

A recent phase II study by our group documented a response rate of 27% with the combination paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) 175 mg/m2 plus carboplatin dosed to a target area under the ...

Article

Paclitaxel plus carboplatin versus paclitaxel plus alternating carboplatin and cisplatin for initial treatment of advanced ovarian cancer: Long-term efficacy results: A Hellenic Cooperative Oncology Group (HeCOG) study

Aravantinos, Gerasimos; Fountzilas, George; Kosmidis, Paraskevas A.; Dimopoulos, M. A.; Stathopoulos, G. P.; Pavlidis, Nicholas; Bafaloukos, Dimitrios; Papadimitriou, C.; Karpathios, S.; Georgoulias, V.; Papakostas, P.; Kalofonos, H. P.; Grimani, E.; Skarlos, Dimosthenis V. (2005)

Background: We compared the combination plus Carboplatin plus paclitaxel, which is considered the treatment of choice for initial chemotherapy of advanced ovarian cancer (AOC) with a regimen combining alternating carboplatin ...

Article

Personality variables as predictors of early non-metastatic colorectal cancer patients' psychological distress and health-related quality of life: A one-year prospective study

Hyphantis, T.; Paika, V.; Almyroudi, A.; Kampletsas, E. O.; Pavlidis, Nicholas (2011)

Objective: We aimed to assess the course of early non-metastatic colorectal cancer patients' psychological distress and health-related quality of life (HRQOL) and to identify relevant clinical and psychological predictors ...

Article

Population pharmacokinetics and dynamics in phase II studies of the novel bioreductive alkylating cytotoxic indoloquinone EO9

Schellens, J. H. M.; Dombernowsky, P.; Cassidy, J.; Epelbaum, R.; Dirix, L.; Cox, E. H.; Wanders, J.; Calabresi, F.; Paridaens, R.; Monfardini, S.; Wolff, J.; Loos, W. J.; Verweij, J.; Pavlidis, Nicholas; Hanauske, A. R. (2001)

Population pharmacokinetic-dynamic analysis was prospectively integrated in the clinical phase II programme of EO9 to determine the population pharmacokinetic profile in a larger population of patients, to estimate individual ...

Article

Prediction of high-risk asymptomatic carotid plaques based on ultrasonic image features

Kyriacou, Efthyvoulos C.; Petroudi, Styliani; Pattichis, Constantinos S.; Pattichis, Marios S.; Griffin, Maura B.; Kakkos, Stavros K.; Nicolaïdes, Andrew N. (2012)

Carotid plaques have been associated with ipsilateral neurological symptoms. High-resolution ultrasound can provide information not only on the degree of carotid artery stenosis but also on the characteristics of the ...

Article

Sense of Coherence and Defense Style Predict Sleep Difficulties in Early Non-metastatic Colorectal Cancer

Hyphantis, T.; Goulia, P.; Zerdes, I.; Solomou, S.; Andreoulakis, E.; Carvalho, A. F.; Pavlidis, Nicholas (2016)

Background: Sleep disturbances are common in cancer patients, but little is known about the complex interplay between the background psychological profile, coping with health stressors capacities and psychological distress ...