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Browsing by Subject "Randomized controlled trials"

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    • Article  

      Effects of different chemotherapy regimens on survival for advanced cervical cancer: Systematic review and meta-analysis 

      Tzioras, S.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2007)
      Background: A large number of trials have assessed various chemotherapy regimens for the treatment of advanced cervical cancer, but there is uncertainty about the magnitude of survival benefits. Methods: We searched (last ...

    • Article  

      Immunomodulation in colorectal cancer: Disappointment or promise? 

      Pentheroudakis, George; Pavlidis, Nicholas (2003)

    • Article  

      Management of leptomeningeal malignancy 

      Pentheroudakis, George; Pavlidis, Nicholas (2005)
      Leptomeningeal carcinomatosis is defined as malignant infiltration of the pia matter and arachnoid membrane. Leukaemias and lymphomas, lung, breast cancer and melanoma are the primary tumours commonly associated with ...

    • Article  

      Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis 

      Mauri, D.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2005)
      Background: Interest in the use of preoperative systemic treatment in the management of breast cancer has increased because such neoadjuvant therapy appears to reduce the extent of local surgery required. We compared the ...

    • Article  

      Prognostic factors in patients with colorectal cancer receiving adjuvant chemotherapy or chemoradiotherapy: A pooled analysis of two randomized studies 

      Bamias, A. T.; Basdanis, G.; Xanthakis, I.; Pavlidis, Nicholas; Fountzilas, George (2005)
      Background. Although the TNM system is useful in predicting survival in resected colorectal cancer, heterogeneity within the same stages regarding prognosis exists. We are presenting a pooled analysis of prognostic factors ...

    • Article  

      Randomized evidence on chemotherapy and hormonal therapy regimens for advanced endometrial cancer: An overview of survival data 

      Polyzos, N. P.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2006)
      Several chemotherapy and hormonal therapy regimens have been used in advanced endometrial cancer. In this review we have systematically evaluated the available data from randomized trials on survival. We searched MEDLINE, ...

    • Article  

      Re: Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis (multiple letters) [2] 

      Popat, S.; Smith, I. E.; Mauri, D.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2005)

    • Article  

      Survival benefits with diverse chemotherapy regimens for ovarian cancer: Meta-analysis of multiple treatments 

      Kyrgiou, M.; Salanti, G.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2006)
      Background: Numerous randomized trials have compared different chemotherapy regimens in women with ovarian cancer. Although ovarian cancer survival has improved in recent years, the magnitude of these incremental benefits ...

    • Article  

      Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: Meta-analysis 

      Mauri, D.; Pavlidis, Nicholas; Polyzos, N. P.; Ioannidis, J. P. A. (2006)
      Background: Aromatase inhibitors and inactivators have been extensively tested in patients with advanced breast cancer, but it is unclear whether they offer any survival benefits compared with standard hormonal treatment ...

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