Browsing by Subject "Randomized controlled trials"

Article

Effects of different chemotherapy regimens on survival for advanced cervical cancer: Systematic review and meta-analysis

Tzioras, S.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2007)

Background: A large number of trials have assessed various chemotherapy regimens for the treatment of advanced cervical cancer, but there is uncertainty about the magnitude of survival benefits. Methods: We searched (last ...

Article

Immunomodulation in colorectal cancer: Disappointment or promise?

Pentheroudakis, George; Pavlidis, Nicholas (2003)

Article

Management of leptomeningeal malignancy

Pentheroudakis, George; Pavlidis, Nicholas (2005)

Leptomeningeal carcinomatosis is defined as malignant infiltration of the pia matter and arachnoid membrane. Leukaemias and lymphomas, lung, breast cancer and melanoma are the primary tumours commonly associated with ...

Article

Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis

Mauri, D.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2005)

Background: Interest in the use of preoperative systemic treatment in the management of breast cancer has increased because such neoadjuvant therapy appears to reduce the extent of local surgery required. We compared the ...

Article

Prognostic factors in patients with colorectal cancer receiving adjuvant chemotherapy or chemoradiotherapy: A pooled analysis of two randomized studies

Bamias, A. T.; Basdanis, G.; Xanthakis, I.; Pavlidis, Nicholas; Fountzilas, George (2005)

Background. Although the TNM system is useful in predicting survival in resected colorectal cancer, heterogeneity within the same stages regarding prognosis exists. We are presenting a pooled analysis of prognostic factors ...

Article

Randomized evidence on chemotherapy and hormonal therapy regimens for advanced endometrial cancer: An overview of survival data

Polyzos, N. P.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2006)

Several chemotherapy and hormonal therapy regimens have been used in advanced endometrial cancer. In this review we have systematically evaluated the available data from randomized trials on survival. We searched MEDLINE, ...

Article

Re: Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis (multiple letters) [2]

Popat, S.; Smith, I. E.; Mauri, D.; Pavlidis, Nicholas; Ioannidis, J. P. A. (2005)

Article

Survival benefits with diverse chemotherapy regimens for ovarian cancer: Meta-analysis of multiple treatments

Kyrgiou, M.; Salanti, G.; Pavlidis, Nicholas; Paraskevaidis, E.; Ioannidis, J. P. A. (2006)

Background: Numerous randomized trials have compared different chemotherapy regimens in women with ovarian cancer. Although ovarian cancer survival has improved in recent years, the magnitude of these incremental benefits ...

Article

Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: Meta-analysis

Mauri, D.; Pavlidis, Nicholas; Polyzos, N. P.; Ioannidis, J. P. A. (2006)

Background: Aromatase inhibitors and inactivators have been extensively tested in patients with advanced breast cancer, but it is unclear whether they offer any survival benefits compared with standard hormonal treatment ...