• Conference Object  

      CFD modeling of turbulent flow and particle deposition in human lungs 

      Radhakrishnan, H.; Kassinos, Stavros C. (Affiliation: UCY-CompSci Computational Sciences Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, CyprusCorrespondence Address: Radhakrishnan, H.UCY-CompSci Computational Sciences Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprusemail: hariradh@ucy.ac.cy, 2009)
      Understanding transport and deposition of inhaled particles in the human airways plays a crucial role in the targeted therapy of pulmonary diseases, and the administration of inhaled medicines. Numerous researchers have ...
    • Article  

      Direct numerical simulation of particle laden flow in a human airway bifurcation model 

      Stylianou, F. S.; Sznitman, J.; Kassinos, Stavros C. (2016)
      During the delivery of inhaled medicines, and depending on the size distribution of the particles in the formulation, airway bifurcations are areas of preferential deposition. Previous studies of laminar flow through airway ...
    • Conference Object  

      The effect of flow rate, head position, and inhaler orientation on the airflow and particle deposition in an mri-based mouth-throat geometry 

      Stylianou, F. S.; Angeli, S.; Kassinos, Stavros C.; Svensson, M. (International Symposium on Turbulence and Shear Flow Phenomena, TSFP10, 2017)
      The mouth-throat plays a key role in the administration of inhaled medicines. It is an area of intense filtration, where an unacceptably high fraction of the released drug dose is deposited and thus wasted. Due to the ...
    • Conference Object  

      Numerical modeling of turbulent airflow and particle deposition in a bifurcating airway model 

      Radhakrishnan, H.; Kassinos, Stavros C. (Affiliation: UCY-CompSci Computational Sciences Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, CyprusCorrespondence Address: Radhakrishnan, H.UCY-CompSci Computational Sciences Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus, 2009)
      Understanding transport and deposition of inhaled particles in the human airways plays a crucial role in the targeted therapy of pulmonary diseases, and the administration of inhaled medicines. Numerous researchers have ...