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Browsing by Subject "Retrospective studies"

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    • Article  

      Advanced stage clear-cell epithelial ovarian cancer: The Hellenic cooperative oncology group experience 

      Pectasides, Dimitrios; Fountzilas, George; Aravantinos, Gerasimos; Kalofonos, H. P.; Efstathiou, E.; Farmakis, D.; Skarlos, Dimosthenis V.; Pavlidis, Nicholas; Economopoulos, T.; Dimopoulos, M. A. (2006)
      Purpose.: Ovarian clear-cell carcinomas (OCCC) are known to be possibly resistant to platinum-based chemotherapy and to have a poorer prognosis with respect to other subtypes of epithelial ovarian cancer (EOC). This study ...

    • Article  

      Alcohol and psychoactive drugs increased the pre-hospital mortality in 655 fall-related fatalities in Greece: A call for management protocols 

      Papadopoulos, I. N.; Bonovas, Stefanos; Kanakaris, Nikolaos K.; Nikolopoulos, Georgios K.; Kotsilianou, Olympia; Konstantoudakis, Georgios; Leukidis, Christos (2012)
      Introduction: The frequency of alcohol and psychoactive drugs in fall-related fatalities and their effect on type, severity of injury and location of death constitute the subjects of this study. Methods: A retrospective ...

    • Article  

      Anthracycline-based chemotherapy of primary non-Hodgkin's lymphoma of the testis: The Hellenic Cooperative Oncology Group experience 

      Pectasides, Dimitrios; Economopoulos, T.; Kouvatseas, G.; Antoniou, A.; Zoumbos, Z.; Aravantinos, Gerasimos; Tsatalas, C.; Halikia, A.; Nikolaides, C.; Kiamouris, Ch; Pappa, E.; Pavlidis, Nicholas; Skarlos, Dimosthenis V.; Fountzilas, George; Dimopoulos, M. A. (2000)
      Testicular non-Hodgkin's lymphoma is an uncommon disease and its outcome following chemotherapy and/or radiotherapy has been variable. A retrospective analysis was performed on 26 patients with primary testicular lymphoma ...

    • Article  

      Assessing the secular trends in the transmission of HIV in Greece 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Masgala, Aikaterini; Paraskeva, D. (2005)
      Objective: To evaluate the current trends in HIV transmission in Greece. Methods: A retrospective study of HIV infected individuals reported to the Hellenic Center for Infectious Diseases Control (HCIDC) was conducted. ...

    • Article  

      Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: Interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes 

      Pentheroudakis, George; Kotoula, V.; Roock, W. De; Kouvatseas, G.; Papakostas, P.; Makatsoris, T.; Papamichael, D.; Xanthakis, I.; Sgouros, J.; Televantou, D.; Kafiri, G.; Tsamandas, A. C.; Razi, E. D.; Galani, E.; Bafaloukos, Dimitrios; Efstratiou, I.; Bompolaki, I.; Pectasides, Dimitrios; Pavlidis, Nicholas; Tejpar, S.; Fountzilas, George (2013)
      Background: More than half of patients with KRAS-wild type advanced colorectal cancer (CRC) fail anti-EGFR monoclonal antibodies. We studied EGFR-axis messenger RNA (mRNA) expression and RAS, RAF, PIK3CA mutations in order ...

    • Article  

      Cancer diagnosis in a cohort of patients with Sjogren's syndrome and rheumatoid arthritis: A single-center experience and review of the literature 

      Boussios, Stergios; Pentheroudakis, George; Somarakis, G.; Markatseli, T. E.; Drosos, Alexandros A.; Pavlidis, Nicholas (2014)
      Background: With the development of modern therapies and better care of patients with autoimmune rheumatic diseases (ARDs) increased survival has been achieved. However, ARDs may share an association with risk of lymphomas ...

    • Article  

      Cancer of unknown primary patients with midline nodal distribution: Midway between poor and favourable prognosis? 

      Pentheroudakis, George; Stoyianni, A.; Pavlidis, Nicholas (2011)
      Background: Midline nodal cancer of unknown primary (CUP) has varying definitions and an unclear natural history compared to that of extragonadal germ cell cancer (EGCC) and neuroendocrine tumors. Methods: We systematically ...

    • Article  

      Cavitating squamous cell lung carcinoma-distinct entity or not? Analysis of radiologic, histologic, and clinical features 

      Pentheroudakis, George; Kostadima, Lida; Fountzilas, George; Kalogera-Fountzila, Anna; Klouvas, G. D.; Kalofonos, H. P.; Pavlidis, Nicholas (2004)
      Introduction: Patients with cavitating squamous lung carcinoma (cSLC) are believed to harbor aggressive, chemoresistant disease with distinct features and fare poorly. We retrospectively analyzed radiologic, histologic, ...

    • Article  

      The clinical picture of primary Sjogren's syndrome: A retrospective study 

      Pavlidis, Nicholas; Karsh, J.; Moutsopoulos, H. M. (1982)
      The clinical and laboratory features of 47 patients with primary Sjogren's syndrome, confirmed by lip biopsy, were analyzed in this study. The majority of our patients had the classical signs and symptoms of Sjogren's ...

    • Article  

      Combination chemotherapy with cisplatin and/or doxorubicin in malignant mesothelioma. A prospective study 

      Tsavaris, N.; Primikirios, N.; Mylonakis, N.; Varouchakis, G.; Dosios, T.; Pavlidis, Nicholas; Skarlos, Dimosthenis V.; Tasopoulos, T.; Dritsas, J.; Kosmidis, Paraskevas A. (1997)
      From June 1984 to October 1995, forty seven consecutive patients (pts) with a confirmed diagnosis of diffuse malignant mesothelioma (MM) of the pleura (41) and peritoneum (6), were treated with cisplatin (CDDP) (24 pts) ...

    • Article  

      Cost-effectiveness of leucoreduction for prevention of febrile non-haemolytic transfusion reactions 

      Tsantes, Argirio E.; Kyriakou, Elias; Nikolopoulos, Georgios K.; Stylos, D.; Sidhom, M.; Bonovas, Stefanos; Douramani, Panagiota; Kalantzis, Dimitrios; Kokoris, Styliani; Valsami, S.; Stamoulis, K.; Politou, M.; Foudoulaki-Paparizos, Leontini (2014)
      Background. The cost-effectiveness of universal leucoreduction of blood components remains unclear. When using leucoreduced red blood cells, the decrease in the rate of febrile non-haemolytic transfusion reactions (FNHTR) ...

    • Article  

      Elderly patients with squamous lung carcinoma: Faring better or worse? 

      Pentheroudakis, George; Neanidis, K.; Kostadima, Lida; Fountzilas, George; Pavlidis, Nicholas (2006)
      Introduction: Nonsmall cell lung cancer is increasingly diagnosed at an advanced age and squamous cell carcinoma is the commonest histological type encountered in older patients. The clinical course, management, and outcome ...

    • Article  

      Epithelial ovarian cancer in Greece: A retrospective study of 1,791 patients by the hellenic cooperative oncology group (HeCOG) 

      Pectasides, Dimitrios; Papaxoinis, G.; Fountzilas, George; Aravantinos, Gerasimos; Bamias, A. T.; Pavlidis, Nicholas; Kalofonos, H. P.; Timotheadou, E.; Samantas, E.; Briassoulis, E. Ch; Skarlos, Dimosthenis V.; Economopoulos, T.; Dimopoulos, M. A. (2009)
      Background: The aim of this retrospective study was to present the epidemiological, pathological and clinical characteristics and treatment results of Greek women with epithelial ovarian cancer (EOC). Patients and Methods: ...

    • Article  

      Evaluation of six tumor markers in patients with carcinoma of unknown primary 

      Pavlidis, Nicholas; Kalef-Ezra, J. A.; Briassoulis, E. Ch; Skarlos, Dimosthenis V.; Kosmidis, Paraskevas A.; Saferiadis, K.; Bairaktari, Eleni Th; Bafaloukos, Dimitrios; Maravegias, A.; Theoharis, D.; Fountzilas, George (1994)
      We have retrospectively evaluated six serum tumor markers in 85 patients with carcinoma of unknown primary. The serum levels of carcinoembryonic antigen (CEA), CA 19‐9, CA 15‐3, CA 125, β‐chorionic gonadotropin (β‐HCG) and ...

    • Article  

      Global microRNA profiling in favorable prognosis subgroups of cancer of unknown primary (CUP) demonstrates no significant expression differences with metastases of matched known primary tumors 

      Pentheroudakis, George; Spector, Y.; Krikelis, D.; Kotoula, V.; Meiri, E.; Malamou-Mitsi, Vassiliki D.; Fountzilas, George; Sanden, M.; Pavlidis, Nicholas; Benjamin, H.; Aharonov, R. (2013)
      No data exist on biologic differences between Cancer of unknown primary (CUP) and metastatic solid tumors of known primary site. We assigned a primary tissue of origin in 40 favorable CUP patients (A: serous peritoneal ...

    • Article  

      High levels of topoisomerase IIα protein expression in diffuse large B-cell lymphoma are associated with high proliferation, germinal center immunophenotype, and response to treatment 

      Pentheroudakis, George; Goussia, Anna; Voulgaris, E.; Nikolaides, C.; Ioannidou, E.; Papoudou-Bai, A.; Grepi, K.; Kanavaros, P.; Pavlidis, Nicholas; Bai, M. C. (2010)
      Gene copy number and protein expression of topoisomerase IIα were correlated to benefit from anthracyclines in various tumors. A retrospective series of 69 patients with DLBCL managed with CHOP chemotherapy were studied ...

    • Article  

      HIV/HBV co-infection and rate of antiretroviral treatment change after highly active antiretroviral treatment initiation in a cohort of HIV-infected patients in Greece 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2010)
      The current study investigated the impact of human immunodeficiency virus (HIV)/hepatitis B virus (HBV) co-infection on the rate of change of antiretroviral drugs after the initiation of highly active antiretroviral treatment ...

    • Article  

      Impact of hepatitis B virus infection on the progression of AIDS and mortality in HIV-infected individuals: A cohort study and meta-analysis 

      Nikolopoulos, Georgios K.; Paraskeva, D.; Hatzitheodorou, E.; Moschidis, Zissis; Sypsa, V.; Zavitsanos, X.; Kalapothaki, Victoria; Hatzakis, A. (2009)
      Background. The effect of hepatitis B virus (HBV) infection on the natural history of human immunodeficiency virus (HIV) disease remains uncertain. Therefore, a retrospective cohort study was conducted to examine the ...

    • Article  

      The impact of iron overload and genotype on gonadal function in women with thalassaemia major 

      Skordis, Nicos; Gourni, Maritsa; Kanaris, Constantinos; Toumba, Meropi; Kleanthous, Marina; Karatzia, Ntina; Pavlidis, Nicholas; Angastiniotis, Michael (2004)
      OBJECTIVE: The purpose of this study is to evaluate the impact of chronic iron overload and genotype on gonadal function in women with thalassaemia major.

    • Article  

      Inflammatory prostate cancer: An underestimated paraneoplastic clinical manifestation 

      Mauri, D.; Pentheroudakis, George; Ch, F. Tolis; Chojnacka, M.; Pavlidis, Nicholas (2005)
      Purpose: To identify the incidence of prostate cancer associated-systemic inflammatory syndrome (SIS), and to characterize further this entity, we searched our database as well as the medical literature. Methods: We ...

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