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Browsing by Subject "Risk factor"

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    • Article  

      Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Rapti, E.; Mantzios, Georgios P.; Kapsimali, Violetta; Travlou, Anthi S. (2007)
      The effect of the 675 insertion/deletion (4G/5G) polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene on the risk of venous thromboembolism (VTE) remains controversial. In this study, we performed a meta-analysis ...

    • Article  

      The beneficial effect of tamoxifen on serum lipoprotein-a levels: An additional anti-atherogenic property 

      Elisaf, Moses S.; Bairaktari, Eleni Th; Nikolaides, C.; Fountzilas, George; Tzallas, C. S.; Siamopoulos, K. C.; Tsolas, O.; Pavlidis, Nicholas (1996)
      It has recently been suggested that increased lipoprotein (a) levels are an independent risk factor for coronary heart disease. It has also been reported that tamoxifen can induce changes in blood lipid values. In this ...

    • Article  

      Bisphosphonate use and risk of colorectal cancer: A systematic review and meta-analysis 

      Bonovas, Stefanos; Nikolopoulos, Georgios K.; Bagos, Pantelis G. (2013)
      Aim: A growing body of evidence suggests that bisphosphonates may have chemopreventive potential against colorectal cancer. Our aim was to examine this association through a meta-analysis of observational studies. Methods: ...

    • Article  

      Cancer of unknown primary site: 20 questions to be answered 

      Pavlidis, Nicholas; Pentheroudakis, George (2010)
      Cancer of unknown primary (CUP) is a common, well-recognized and heterogeneous clinical syndrome. Patients with CUP present with metastatic disease in the absence of an identifiable primary tumour despite a diagnostic ...

    • Article  

      Cefditoren: Comparative efficacy with other antimicrobials and risk factors for resistance in clinical isolates causing UTIs in outpatients 

      Hatzaki, Despina; Poulakou, G.; Katsarolis, Ioannis; Lambri, Niki; Souli, M.; Deliolanis, Ioannis; Nikolopoulos, Georgios K.; Lebessi, Evangelia; Giamarellou, Helen (2012)
      Background: To investigate a possible role of Cefditoren, a recently marketed in Greece third-generation oral cephalosporin in urinary infections of outpatients.Methods: During a multicenter survey of Enterobacteriaceae ...

    • Article  

      Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: The ARISTOTLE programme 

      Hatzakis, A.; Sypsa, V.; Paraskeva, D.; Nikolopoulos, Georgios K.; Tsiara, Chrissa G.; Micha, Katerina; Panopoulos, A.; Malliori-Minerva, Melpomeni; Psichogiou, M.; Pharris, Anastasia; Wiessing, L.; Laar, M. J. van de; Donoghoe, Martin; Heckathorn, Douglas D.; Friedman, Samuel R.; Jarlais, Don C. Des (2015)
      Aims: To (i) describe an intervention implemented in response to the HIV-1 outbreak among people who inject drugs (PWIDs) in Greece (ARISTOTLE programme), (ii) assess its success in identifying and testing this population ...

    • Article  

      Developing the evidence base for cancer chemoprevention: Use of meta-analysis 

      Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Bonovas, Stefanos (2011)
      Meta-analysis is a quantitative approach for systematically combining the results of previous studies in order to arrive at conclusions about the body of research. It answers a specific research question, includes an ...

    • Article  

      Effect of letrozole on the lipid profile in postmenopausal women with breast cancer 

      Elisaf, Moses S.; Bairaktari, Eleni Th; Nikolaides, C.; Kakaidi, B.; Tzallas, C. S.; Katsaraki, A.; Pavlidis, Nicholas (2001)
      Hormonal therapy plays a central role in the overall treatment of breast cancer. Aromatase inhibitors can inhibit the aromatase enzyme system resulting in a reduction of oestrogens. Letrozole is a non-steroidal aromatase ...

    • Article  

      Effects of hormonal treatment on lipids in patients with cancer 

      Filippatos, T. D.; Liberopoulos, E. N.; Pavlidis, Nicholas; Elisaf, Moses S.; Mikhailidis, Dimitri P. (2009)
      Patients with malignant disease may need hormonal therapy as primary or adjuvant treatment or for palliation. Oestrogens usually decrease serum levels of total cholesterol (TC) and low density lipoprotein cholesterol ...

    • Article  

      Efficacy and safety of more intensive lowering of LDL cholesterol [1] 

      Bonovas, Stefanos; Nikolopoulos, Georgios K.; Sitaras, N. M. (2011)

    • Article  

      ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of non-small-cell lung cancer (NSCLC) 

      Felip, E.; Stahel, R. A.; Pavlidis, Nicholas (2005)

    • Article  

      ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) 

      Felip, E.; Pavlidis, Nicholas; Stahel, R. A. (2005)

    • Article  

      Evaluation of thermal discomfort in Athens territory and its effect on the daily number of recorded patients at hospitals' emergency rooms 

      Pantavou, K. G.; Theoharatos, G.; Nikolopoulos, Georgios K.; Katavoutas, G.; Asimakopoulos, D. (2008)
      Previous research has shown that temperature and humidity affect human health. However, only a few studies have examined the association of a biometeorological index, which combines several meteorological parameters and ...

    • Article  

      High-burden epidemics in Greece in the era of economic crisis. Early signs of a public health tragedy 

      Bonovas, Stefanos; Nikolopoulos, Georgios K. (2012)
      Background. Economic hardships have unleashed epidemics of infectious diseases in many countries in the past. In the era of the current financial crisis in Greece, it is interesting to assess the preliminary evidence ...

    • Article  

      Lack of association between endothelial nitric oxide synthase gene polymorphisms and risk of premature coronary artery disease in the Greek population 

      Vasilakou, M.; Votteas, V.; Kasparian, C.; Pantazopoulos, N.; Dedoussis, George V. Z.; Constantinou-Deltas, Constantinos D.; Nastos, P.; Nikolakis, D.; Lamnissou, Klea (2008)
      Objective - Genetic polymorphisms in the gene for endothelial nitric oxide synthase have been considered as potential risk factors for the development of coronary artery disease in some populations. Methods - We studied ...

    • Article  

      Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and coronary artery disease: A meta-analysis 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Vaiopoulos, G.; Travlou, Anthi S. (2007)
      Background: The platelet-collagen receptor, glycoprotein (GP) la/lla plays a crucial role in the adhesion of platelets to fibrillar collagen, an event contributing to the pathogenesis of thrombosis. The C807T polymorphism ...

    • Article  

      Late toxicity in survivors from adolescent cancers 

      Pentheroudakis, George; Pavlidis, Nicholas (2007)
      Nowadays three quarters of adolescents with cancer are cured but half of them experience a late toxic effect of antineoplastic therapy that interferes with their physical and psychosocial health. This review recapitulates ...

    • Article  

      Maltreatment Profiles Among Incarcerated Boys With Callous-Unemotional Traits 

      Kimonis, Eva R.; Fanti, Kostas A.; Isoma, Zachary; Donoghue, Kathleen (2013)
      Callous-unemotional (CU) traits in youth are believed to be a developmental precursor to adult psychopathy, tapping its affective dimension. There is growing support for the existence of variants of psychopathy that can ...

    • Article  

      Management of leptomeningeal malignancy 

      Pentheroudakis, George; Pavlidis, Nicholas (2005)
      Leptomeningeal carcinomatosis is defined as malignant infiltration of the pia matter and arachnoid membrane. Leukaemias and lymphomas, lung, breast cancer and melanoma are the primary tumours commonly associated with ...

    • Article  

      Network characteristics of people who inject drugs within a new HIV epidemic following austerity in Athens, Greece 

      Tsang, M. A.; Schneider, J. A.; Sypsa, V.; Schumm, P.; Nikolopoulos, Georgios K.; Paraskeva, D.; Friedman, Samuel R.; Malliori-Minerva, Melpomeni; Hatzakis, A. (2015)
      Background: Greece experienced an unprecedented increase in HIV cases among drug injectors in 2011 after economic crisis. Network-level factors are increasingly understood to drive HIV transmission in emerging epidemics. ...

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