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Browsing by Subject "Systemic therapy"

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    • Article  

      Beyond triple-negative breast cancer: The need to define new subtypes 

      Constantinidou, Anastasia; Jones, Robin Lewis; Reis-Filho, J. S. (2010)
      Advances in the systemic treatment of early breast cancer have led to significant improvements in survival for patients with hormone receptor- and/or HER2-positive disease. In recent years, interest has focused on tumors ...

    • Article  

      Cancer and pregnancy: What should we know about the management with systemic treatment of pregnant women with cancer? 

      Pavlidis, Nicholas (2011)
      The incidence of cancer during pregnancy is a rare phenomenon and is estimated to occur in 1:1000 pregnancies. This co-existence is likely to rise since the delay of childbearing to the later reproductive age is nowadays ...

    • Article  

      Cancer of unknown primary during pregnancy: An exceptionally rare coexistence 

      Pavlidis, Nicholas; Peccatori, Fedro A.; Lofts, F.; Greco, F. A. (2015)
      Background: Cancer in pregnancy is a rare disease with breast cancer, cervical cancer, melanoma and Hodgkin's disease to be the most commonly diagnosed malignancies during gestation. Cancer of unknown primary (CUP) is a ...

    • Article  

      Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up 

      Peccatori, Fedro A.; Azim, Hatem A.; Orecchia, R.; Hoekstra, H. J.; Pavlidis, Nicholas; Kesic, V.; Pentheroudakis, George (2013)

    • Article  

      Clinical trial design methodologies for advanced sarcoma therapy 

      Petek, B. J.; Pollack, S. M.; Constantinidou, Anastasia; Jones, Robin Lewis (2015)
      Sarcomas are rare and heterogeneous mesenchymal tumors affecting connective tissue. For many years, doxorubicin-based chemotherapy has been the main systemic therapy option for patients with metastatic soft tissue sarcoma. ...

    • Article  

      The diagnostic and therapeutic management of leptomeningeal carcinomatosis 

      Pavlidis, Nicholas (2004)

    • Article  

      The evolution of systemic therapy in sarcoma 

      Constantinidou, Anastasia; Pollack, S. M.; Loggers, Elizabeth; Rodler, E.; Jones, Robin Lewis (2013)
      Approximately 50% of patients with localized soft tissue sarcomas will develop recurrent disease after complete surgical resection, requiring alternative means of treatment. Conventional chemotherapy comprising of doxorubicin ...

    • Article  

      Lung cancer in pregnancy: Report of nine cases from an international collaborative study 

      Boussios, Stergios; Han, S. N.; Fruscio, R.; Halaska, M. J.; Ottevanger, P. B.; Peccatori, Fedro A.; Koubková, L.; Pavlidis, Nicholas; Amant, F. (2013)
      Objective: Lung cancer is an uncommon diagnosis during pregnancy. The combination of smoking in young women, increased maternal age during pregnancy, and increasing incidence of lung cancer worldwide may cause an increase ...

    • Article  

      Lung cancer in the pregnant woman: To treat or not to treat, that is the question 

      Jr, H. A. Azim; Peccatori, Fedro A.; Pavlidis, Nicholas (2010)
      Lung cancer in pregnancy is a rare situation; however, it is increasingly reported in the past two decades. The association might be more encountered in the coming years due to the rising trends of cigarette smoking among ...

    • Article  

      New drugs and clinical trial design in advanced sarcoma: Have we made any progress? 

      Constantinidou, Anastasia; Miah, Aisha; Pollack, S. M.; Jones, Robin Lewis (2013)

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