• Article  

      Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Rapti, E.; Mantzios, Georgios P.; Kapsimali, Violetta; Travlou, Anthi S. (2007)
      The effect of the 675 insertion/deletion (4G/5G) polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene on the risk of venous thromboembolism (VTE) remains controversial. In this study, we performed a meta-analysis ...
    • Article  

      The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis 

      Tsantes, Argirio E.; Tsangaris, I.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Kopterides, Petros; Antonakos, Georgios; Dimopoulou, Ioanna; Vrioni, G.; Kapsimali, Violetta; Dima, Kleanthi; Armaganidis, Apostolos; Travlou, Anthi S. (2010)
      Background. There is considerable evidence that elevated plasma homocysteine levels are associated with a prothrombotic milieu, whereas activation of the coagulation cascade is an important component of the pathogenesis ...
    • Article  

      Prevalence of genetic mutations that predispose to thrombophilia in a Greek Cypriot population 

      Angelopoulou, Katerina; Nicolaïdes, Andrew N.; Constantinou-Deltas, Constantinos D. (2000)
      Several hereditary disorders, particularly those affecting the physiological anticoagulation systems, have been well established as risk factors for venous thromboembolism. In the present study, we investigated the prevalence ...
    • Article  

      Spectrum and prevalence of prothrombotic single nucleotide polymorphism profiles in the Greek Cypriot population 

      Xenophontos, Stavroulla L.; Hadjivassiliou, Marilena; Ayrton, N.; Karagrigoriou, Alex; Pantzaris, Marios C.; Nicolaïdes, Andrew N.; Cariolou, Marios A. (2002)
      Background. This study was performed to establish the allele, genotype and genotype combination/SNP (single nucleotide polymorphism) profile frequencies in the general population of Cyprus for 6 genes implicated in thrombotic ...