Browsing by Subject "Trabectedin"
Now showing items 1-4 of 4
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Article
Advanced soft-tissue sarcoma and treatment options: Critical appraisal of trabectedin
(2016)Soft-tissue sarcomas (STS) are a heterogeneous group of rare solid tumors of mesenchymal origin. This paper reviews the current status of systemic treatment in advanced and metastatic soft tissue sarcomas, with an emphasis ...
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Article
The evolution of systemic therapy in sarcoma
(2013)Approximately 50% of patients with localized soft tissue sarcomas will develop recurrent disease after complete surgical resection, requiring alternative means of treatment. Conventional chemotherapy comprising of doxorubicin ...
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Article
Trabectedin in advanced synovial sarcomas: A multicenter retrospective study from four European institutions and the Italian Rare Cancer Network
(2015)Treatment options for patients with metastatic synovial sarcoma are limited. Over recent years, trabectedin has emerged as an effective agent for patients with advanced soft tissue sarcomas resistant to anthracyclines and ...
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Article
Trabectedin-related rhabdomyolysis: An uncommon but fatal toxicity
(2011)Rhabdomyolysis is defined as the dissolution of striped muscle characterized by the leakage of intracellular muscle components into the circulation, which can ultimately lead to renal failure with a possible fatal outcome. ...