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Browsing by Subject "Unknown primary"

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    • Article  

      Age-Dependent Metastatic Spread and Survival: Cancer of Unknown Primary as a Model 

      Hemminki, K.; Pavlidis, Nicholas; Tsilidis, K. K.; Sundquist, K.; Ji, J. (2016)
      In order to describe a novel approach for the clinical study of metastases, we provide here age-specific incidence and survival data for cancer of unknown primary (CUP). Metastases in various organs are found at CUP ...

    • Article  

      Angiogenesis in cancer of unknown primary: Clinicopathological study of CD34, VEGF and TSP-1 

      Karavasilis, V.; Malamou-Mitsi, Vassiliki D.; Briassoulis, E. Ch; Tsanou, E.; Kitsou, E.; Kalofonos, H. P.; Fountzilas, George; Fotsis, T.; Pavlidis, Nicholas (2005)
      Background: Cancer of unknown primary remains a mallignancy of elusive biology and grim prognosis that lacks effective therapeutic options. We investigated angiogenesis in cancer of unknown primary to expand our knowledge ...

    • Article  

      Axillary nodal metastases from carcinoma of unknown primary (CUPAx): A systematic review of published evidence 

      Pentheroudakis, George; Lazaridis, G.; Pavlidis, Nicholas (2010)
      Axillary lymph node metastases from adenocarcinoma or poorly differentiated carcinoma of unknown primary (CUPAx) represent a rare clinical entity without consensus on its biology, management and outcome. We systematically ...

    • Article  

      Brain metastasis of unknown primary: A diagnostic and therapeutic dilemma 

      Polyzoidis, K. S.; Miliaras, G.; Pavlidis, Nicholas (2005)
      The diagnosis of a brain metastasis is usually made during the routine follow up examinations of patients with known cancer, who are under the care of oncology departments. The involvement of the neurosurgeon depends on ...

    • Article  

      Cancer of unknown primary during pregnancy: An exceptionally rare coexistence 

      Pavlidis, Nicholas; Peccatori, Fedro A.; Lofts, F.; Greco, F. A. (2015)
      Background: Cancer in pregnancy is a rare disease with breast cancer, cervical cancer, melanoma and Hodgkin's disease to be the most commonly diagnosed malignancies during gestation. Cancer of unknown primary (CUP) is a ...

    • Article  

      Cancer of unknown primary origin 

      Briassoulis, E. Ch; Pavlidis, Nicholas (1997)
      About 3 % of all cancer patients suffer from cancer of unknown primary origin. These patients present with metastatic disease for which a primary site cannot be detected at the time of diagnosis. Sophisticated diagnostic ...

    • Article  

      Cancer of Unknown Primary origin in the genomic era: Elucidating the dark box of cancer 

      Economopoulou, P.; Mountzios, G.; Pavlidis, Nicholas; Pentheroudakis, George (2015)
      Cancer of Unknown Primary (CUP) comprises a heterogeneous disease group with diagnosis of metastatic malignancy in the absence of an identifiable primary site after diagnostic work up. CUP may either resemble a specific ...

    • Article  

      Cancer of unknown primary patients with midline nodal distribution: Midway between poor and favourable prognosis? 

      Pentheroudakis, George; Stoyianni, A.; Pavlidis, Nicholas (2011)
      Background: Midline nodal cancer of unknown primary (CUP) has varying definitions and an unclear natural history compared to that of extragonadal germ cell cancer (EGCC) and neuroendocrine tumors. Methods: We systematically ...

    • Article  

      Cancer of unknown primary site 

      Pavlidis, Nicholas; Pentheroudakis, George (2012)
      Cancer of unknown primary site (CUP) is a well recognised clinical disorder, accounting for 3-5 of all malignant epithelial tumours. CUP is clinically characterised as an aggressive disease with early dissemination. ...

    • Article  

      Cancer of unknown primary site: 20 questions to be answered 

      Pavlidis, Nicholas; Pentheroudakis, George (2010)
      Cancer of unknown primary (CUP) is a common, well-recognized and heterogeneous clinical syndrome. Patients with CUP present with metastatic disease in the absence of an identifiable primary tumour despite a diagnostic ...

    • Article  

      Cancer of unknown primary site: Missing primary or missing biology? 

      Pentheroudakis, George; Briassoulis, E. Ch; Pavlidis, Nicholas (2007)
      Cancer of unknown primary site (CUP) ranks as the fourth most common cause of cancer deaths and represents both a diagnostic and a management challenge. In CUP, the regression or dormancy of the primary tumor, the development ...

    • Article  

      Cancer of unknown primary: Biological and clinical characteristics 

      Pavlidis, Nicholas (2003)

    • Article  

      Cancer of unknown primary: What kind of chemotherapy? what kind of disease? 

      Pentheroudakis, George; Pavlidis, Nicholas (2009)

    • Article  

      Cancers of unknown primary site: ESMO clinical practice guidelines for diagnosis, treatment and follow-up 

      Fizazi, K.; Greco, F. A.; Pavlidis, Nicholas; Pentheroudakis, George (2011)

    • Article  

      Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up 

      Fizazi, K.; Greco, F. A.; Pavlidis, Nicholas; Daugaard, G.; Oien, K.; Pentheroudakis, George; ESMO Guidelines Committee (2015)

    • Article  

      Cancers of unknown primary site: ESMO clinical practice guidelines for diagnosis, treatment and follow-up 

      Pavlidis, Nicholas; Briassoulis, E. Ch; Pentheroudakis, George (2010)

    • Article  

      Cancers of unknown primary site: ESMO clinical recommendation for diagnosis, treatment and follow-up 

      Briassoulis, E. Ch; Pavlidis, Nicholas; Felip, E. (2008)

    • Article  

      Cancers of unknown primary site: ESMO Clinical Recommendations for diagnosis, treatment and follow-up 

      Briassoulis, E. Ch; Pavlidis, Nicholas (2007)

    • Article  

      Carboplatin plus paclitaxel in unknown primary carcinoma: A phase II Hellenic Cooperative Oncology Group Study 

      Briassoulis, E. Ch; Kalofonos, H. P.; Bafaloukos, Dimitrios; Samantas, E.; Fountzilas, George; Xiros, N.; Skarlos, Dimosthenis V.; Christodoulou, C.; Kosmidis, Paraskevas A.; Pavlidis, Nicholas (2000)
      Purpose: To evaluate the efficacy of the carboplatin/paclitaxel combination in patients with carcinoma of unknown primary site (CUP). Patients and Methods: Seventy-seven consecutive CUP patients (45 women and 32 men; median ...

    • Article  

      Carcinoma of unknown primary (CUP) 

      Pavlidis, Nicholas; Fizazi, K. (2009)
      Carcinoma of unknown primary (CUP) is one of the 10 most frequent cancers worldwide. It constitutes 3-5% of all human malignancies. Patients with CUP present with metastases without an established primary site. CUP manifests ...

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