Browsing by Subject "Vascular normalization"
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Article
Remodeling components of the tumor microenvironment to enhance cancer therapy
(2015)Solid tumor pathophysiology is characterized by an abnormal microenvironment that guides tumor progression and poses barriers to the efficacy of cancer therapies. Most common among tumor types are abnormalities in the ...
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Article
Stress alleviation strategy in cancer treatment: Insights from a mathematical model
(2018)Tumors generate mechanical forces during growth and progression, which are able to compress blood and lymphatic vessels, reducing perfusion rates and creating hypoxia. Tumor vessels-while nourishing the tumor-are usually ...