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Browsing by Subject "Very elderly"

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    • Article  

      Age-Dependent Metastatic Spread and Survival: Cancer of Unknown Primary as a Model 

      Hemminki, K.; Pavlidis, Nicholas; Tsilidis, K. K.; Sundquist, K.; Ji, J. (2016)
      In order to describe a novel approach for the clinical study of metastases, we provide here age-specific incidence and survival data for cancer of unknown primary (CUP). Metastases in various organs are found at CUP ...

    • Article  

      Cancer prevalence and mortality in centenarians: A systematic review 

      Pavlidis, Nicholas; Stanta, G.; Audisio, R. A. (2012)
      Life expectancy has dramatically expanded, the global population has aged unprecedentedly and the number of centenarians has significantly increased. The analysis of autopsy series, cancer registries data, vital statistics ...

    • Article  

      Insights into the epithelial mesenchymal transition phenotype in cancer of unknown primary from a global microRNA profiling study 

      Stoyianni, A.; Pentheroudakis, George; Benjamin, H.; Cervantes, A.; Ashkenazi, K.; Lazaridis, G.; Pavlidis, Nicholas; Spector, Y. (2014)
      Purpose: We sought to study the microRNA regulation of epithelial mesenchymal transition (EMT), the acquisition of migratory, mesenchymal-like properties of epithelial cells, in cancer of unknown primary (CUP). Patients ...

    • Article  

      Prognostic factors in glioblastoma patients managed with radiotherapy combined with temozolomide 

      Peponi, Evangelia; Toumpoulis, Ioannis K.; Tasiou, I.; Pavlidis, Nicholas; Pentheroudakis, George; Tsekeris, P. (2014)
      Purpose: No consensus on clinicopathologic prognostic factors that predict the outcome of patients with newly diagnosed glioblastoma multiforme (GBM) managed with resection, postoperative radiotherapy (RT) and adjuvant ...

    • Article  

      Prognostic significance of WNT and hedgehog pathway activation markers in cancer of unknown primary 

      Fotopoulos, George; Goussia, Anna; Bareta, E.; Koumpis, E.; Chrisafi, S.; Bobos, M.; Malamou-Mitsi, Vassiliki D.; Fountzilas, George; Pavlidis, Nicholas; Pentheroudakis, George (2015)
      Background: Cancer of unknown primary (CUP) possesses distinct biology and peculiar natural history, in which the roles of the winged and hedgehog signalling pathways are unclear. Materials and methods: We constructed ...

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