Browsing by Subject "adaptation"
Now showing items 1-3 of 3
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Article
Global genetic variation of HIV-1 infection
(2006)Variability, both at the population (interhost) as well as at the individual (intrahost) level is a key property of HIV that stems mainly from the inherent infidelity of the reverse transcriptase enzyme that the virus uses ...
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Article
A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis
(2013)Background: The unfolded protein response (UPR) is a major signalling cascade acting in the quality control of protein folding in the endoplasmic reticulum (ER). The cascade is known to play an accessory role in a range ...
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Article
On learning time delays between the spikes from different input neurons in a biophysical model of a pyramidal neuron
(2015)Biological systems are able to recognise temporal sequences of stimuli or compute in the temporal domain. In this paper we are exploring whether a biophysical model of a pyramidal neuron can detect and learn systematic ...